Gio
18
Apr
Altri Eventi
Organs-on-chip: the electro-mechanical perspective
On Thursday, 18 April 2024 a new appointment of the Thursday Seminar cycle will be held online, entitled "Organs-on-chip: the electro-mechanical perspective", organised by the Institute of Electronics, Computer and Telecommunication Engineering (CNR-IEIIT).
Abstract
Organ-on-chip (OoC) technology is rapidly being established as a valid approach to develop in-vitro models of human (patho)physiology of unprecedented relevance. Advances in the technology involve co-development of the biological substrates and the design of supporting hardware enabling eminently microfluidic perfusion, electro-mechanical actuation and electro-chemical sensing. In this lecture, will introduce the perspective of fully-electric OoCs and of OoC platforms, meant to foster ease of use, wider adoption and superior reproducibility of the technology. Will argue that virtually all relevant functions in OoCs can be driven and controlled electro-mechanically, and exemplify how this is best achieved by a seamless integration of electric and fluidic layers in the architecture of the platforms.
Speaker: professor Massimo Mastrangeli - Delft University of Technology
Abstract
Organ-on-chip (OoC) technology is rapidly being established as a valid approach to develop in-vitro models of human (patho)physiology of unprecedented relevance. Advances in the technology involve co-development of the biological substrates and the design of supporting hardware enabling eminently microfluidic perfusion, electro-mechanical actuation and electro-chemical sensing. In this lecture, will introduce the perspective of fully-electric OoCs and of OoC platforms, meant to foster ease of use, wider adoption and superior reproducibility of the technology. Will argue that virtually all relevant functions in OoCs can be driven and controlled electro-mechanically, and exemplify how this is best achieved by a seamless integration of electric and fluidic layers in the architecture of the platforms.
Speaker: professor Massimo Mastrangeli - Delft University of Technology