Full Professor (L. 240)
Department of Mechanical and Aerospace Engineering (DIMEAS)
- Member of Interdepartmental Center PolitoBIOMed Lab - Biomedical Engineering Lab
- Substitute member Research Ethics Committee (ARI)
Profile
Research interests
Biography
Valeria Chiono has a Master Degree cum laude in Chemical Engineering and a PhD in Chemical and Materials Engineering from the University of Pisa, Italy. She is currently Full Professor at the Department of Mechanical and Aerospace Engineering of Politecnico di Torino, Italy. Her research is aimed at the design of innovative bioengineering approaches to solve key problems in regenerative medicine and nanomedicine, and includes the development of bioactive materials and interfaces, tissue engineering, materials characterization, in vitro tissue models, drug delivery and non-viral gene therapy. One main research topic is cardiac tissue engineering. She has been the coordinator of several research projects, including STARIGEN FIRB2010 project, financed by the Italian Ministry of Education, University and Research, on the preparation of biomimetic scaffolds for cardiac regeneration. In 2017 she has been granted the ERC Consolidator project BIORECAR (contract number: 772168; http://www.biorecar.polito.it/) on advanced strategies for cardiac regeneration by direct reprogramming of fibroblasts into cardiomyocytes by an injectable hydrogel releasing miRNA-loaded nanoparticles. In BIORECAR in vitro models of fibrotic human cardiac tissue are also developed for preclinical investigation. Furthermore, she manages BIORECAR Cell Laboratory at Politecnico di Torino. She is the main lecturer of the following courses at the Faculty of Biomedical Engineering at Politecnico di Torino: “Engineering for regenerative medicine”, “Cell and tissue engineering” and “Laboratory of Tissues and Physiological Processes' Models”. In 2021, she has been appointed Vice-Director of Centro 3R. She is in the editorial board of journals such as Frontiers in Bioengineering and Biotechnology and Biomedical Materials. She is author of 122 scientific publications (H-index/citations: 31/4617 Scopus; 36/6253 Google Scholar) and 5 patents in the field of biomaterials, tissue engineering and nanomedicine.
Curriculum
Scientific branch
(Area 0009 - Industrial and information engineering)
Research topics
- Antimicrobial coatings based on bacterial biosurfactants or biomimetic strategies
- Cardiac tissue engineering: design of biomimetic scaffolds for a stem cells-based therapy in cardiac regeneration
- Design of biomimetic materials by the preparation of bioartificial blends or surface functionalization of synthetic polymer scaffolds with bioactive molecules.
- Direct cell reprogramming applied to cardiac regeneration: preparation of nanoparticles for oligonucleotide release and injectable hydrogels for an in situ therapy of infarcted cardiac tissue.
- Drug releasing hydrogels: preparation of hydrogels based on synthetic and/or natural polymers encapsulating drugs for a controlled and sustained release.
- In vitro tissue models: blood brain barrier and blood vessels on a chip; engineered cardiac fibrotic tissue; healthy and pathological (mimicking chronic wounds) skin tissue
- Non-viral gene therapy: lipid and/or polymer nanoparticles for the release of oligonucleotide agents (e.g., siRNAs and miRNAs)
- Preparation of systems for drug release by green technologies, making use of polymers prepared by bacterial fermentation on by-products of the food industry, or derived from waste products from agricolture, and avoiding or minimizing the use of organic solvents.
Skills
ERC sectors
SDG
Awards and Honors
- BioPmed Award 2014 - Gold conferred by BioPmed (2014)
- Back Cover in Advanced Healthcare Materials conferred by Advanced Healthcare Materials - Wiley (2020)
Fellowships
- Founding partner - ERC in ITALY, Italia (2021-)
- Steering Committe member - Centro Interuniversitario per la Promozione dei Principi delle 3R nella Didattica e nella Ricerca (Centro 3R), Italia (2019-)
- Founding partner - Gruppo Nazionale di Bioingegneria, Italia (2019-)
- Effective member - European Society of Cardiology (ESC), Europeo (2018-)
- Effective member - European Society for Biomaterials, ESB, Europeo (2018-)
- Effective member - TERMIS-EU, Europeo (2012-)
Editorial boards
- MICRO (2021-), Editorial board member
- FRONTIERS IN BIOMATERIALS SCIENCE (2021-), Other editorial activities
- FRONTIERS IN PHARMACOLOGY (2021-), Other editorial activities
- BIOMEDICAL MATERIALS (2020-), Editorial board member
- FRONTIERS IN CARDIOVASCULAR MEDICINE (2020-), Other editorial activities
- FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY (2018-), Associate Editor of magazine or editorial series
- 4 OPEN (2018-), Editorial board member
- BIOMEDICAL SCIENCE AND ENGINEERING (2016-), Director
Conferences
- I Convegno Nazionale SIOoC2023 (4/5/2023-5/5/2023), Program committee
- International Congress on Biofabrication 2022 (1/1/2022-28/9/2022), Program chair
- III Convegno Annuale "L'era delle 3R: modelli in silico, in vitro e in vivo per promuovere la ricerca traslazionale" (30/9/2021-1/10/2021), Chairman of the organizing committee
- XL Scuola Annuale di Bioingegneria 2021 “Biofabrication: an integrated bioengineering approach for the automated fabrication of biological structures for clinical and research applications” (13/9/2021-16/9/2021), Participation to the organizing committee
- CANCERTO - "Nanoscience in Cancer Immunotherapy" (9/3/2021-11/3/2021), Participation to the organizing committee
- Workshop “Biology and bioengineering tools in the treatment of H2020 age-related diseases”, Chairman of the organizing committee
- Workshop "Engineered Biomaterials and Biomedical Devices in the Regenerative Medicine of the Nervous System" (19/11/2015-20/11/2015), Chairman of the organizing committee
- CONGRESSO SOCIETÀ ITALIANA BIOMATERIALI 2013 (3/6/2013-5/6/2013), Participation to the organizing committee
Other titles
- Membro della Giunta DIMEAS 2019-2023 (2019-)
- Referente di Ateneo per l'Azione del PNRR: Centro Nazionale 3 "Sviluppo di terapia genica e farmaci con tecnologia a RNA" (2021-)
- Valutazione carriere per studenti che accedono alla Laurea Magistrale in Ingegneria Biomedica - Politecnico di Torino (2021-)
- Commissario per l'Abilitazione Scientifica Nazionale (ASN) - Settore Concorsuale 09/G2 - Bioingegneria (2021-)
- Tutor accademico di studenti Erasmus Incoming - Facoltà di Ingegneria Biomedica, Politecnico di Torino (2016-2021)
Research networks
Roles as evaluator or expert
- First Call of the ADMIRE Marie Skłodowska-Curie Action COFUND in Advanced Materials Research.. 2021
TRINITY COLLEGE DUBLIN - REMOTE REVIEW ERC GRANTS. 2021
ERC - EUROPEAN RESEARCH COUNCIL - EXECUTIVE AGENCY - REMOTE REVIEW ERC GRANTS. 2020
ERC - EUROPEAN RESEARCH COUNCIL - EXECUTIVE AGENCY
Non-commercial collaboration agreements
- CENTRO 3R - Convenzione per il funzionamento del Centro Interuniversitario per la promozione dei principi delle 3R nella didattica e nella ricerca (CENTRO 3R), (2024-2033) - Responsabile contrattuale
Inter-university centres - Adesione al Centro Interuniversitario per la Promozione dei Principi delle 3R nella didattica e nella ricerca - CENTRO 3R, (2019-2023) - Responsabile Scientifico
Inter-university centres
Teaching
Collegi of the PhD programmes
- BIOINGEGNERIA E SCIENZE MEDICO-CHIRURGICHE, 2022/2023 (39. ciclo)
Politecnico di TORINO - BIOINGEGNERIA E SCIENZE MEDICO-CHIRURGICHE, 2021/2022 (38. ciclo)
Politecnico di TORINO - BIOINGEGNERIA E SCIENZE MEDICO-CHIRURGICHE, 2020/2021 (37. ciclo)
Politecnico di TORINO - BIOINGEGNERIA E SCIENZE MEDICO-CHIRURGICHE, 2019/2020 (36. ciclo)
Politecnico di TORINO - BIOINGEGNERIA E SCIENZE MEDICO-CHIRURGICHE, 2018/2019 (35. ciclo)
Università degli Studi di TORINO - BIOINGEGNERIA E SCIENZE MEDICO-CHIRURGICHE, 2017/2018 (34. ciclo)
Università degli Studi di TORINO - BIOINGEGNERIA E SCIENZE MEDICO-CHIRURGICHE, 2016/2017 (33. ciclo)
Università degli Studi di TORINO - BIOINGEGNERIA E SCIENZE MEDICO-CHIRURGICHE, 2015/2016 (32. ciclo)
Politecnico di TORINO - BIOINGEGNERIA E SCIENZE MEDICO-CHIRURGICHE, 2014/2015 (31. ciclo)
Politecnico di TORINO - BIOINGEGNERIA E SCIENZE MEDICO-CHIRURGICHE, 2013/2014 (30. ciclo)
Politecnico di TORINO
Collegi of the degree programmes
- Collegio di Ingegneria Biomedica. Componente
Teachings
PhD
- Molecular Regulation of Biomaterial, Cell/Tissue Interactions, Mechanisms to Prevent Implant Failure (didattica di eccellenza). A.A. 2022/23, BIOINGEGNERIA E SCIENZE MEDICO-CHIRURGICHE. Main teacher
- Terapie avanzate (nanomedicina, terapia genica e cellulare) in chirurgia. A.A. 2018/19, BIOINGEGNERIA E SCIENZE MEDICO-CHIRURGICHE. Teaching assistant
Master of Science
- Biomimetic systems. A.A. 2024/25, INGEGNERIA BIOMEDICA. Collaboratore del corso
- Ingegneria per la medicina rigenerativa/Bioreattori (modulo di Ingegneria per la medicina rigenerativa). A.A. 2024/25, INGEGNERIA BIOMEDICA. Titolare del corso
- Laboratory of Tissues and Physiological Processes' Models. A.A. 2024/25, INGEGNERIA BIOMEDICA. Titolare del corso
- Sistemi biomimetici. A.A. 2023/24, INGEGNERIA BIOMEDICA. Collaboratore del corso
- Ingegneria per la medicina rigenerativa/Bioreattori (modulo di Ingegneria per la medicina rigenerativa). A.A. 2023/24, INGEGNERIA BIOMEDICA. Titolare del corso
- Laboratory of Tissues and Physiological Processes' Models. A.A. 2023/24, INGEGNERIA BIOMEDICA. Titolare del corso
- Sistemi biomimetici. A.A. 2022/23, INGEGNERIA BIOMEDICA. Collaboratore del corso
- Ingegneria per la medicina rigenerativa/Bioreattori (modulo di Ingegneria per la medicina rigenerativa). A.A. 2022/23, INGEGNERIA BIOMEDICA. Titolare del corso
- Laboratory of Tissues and Physiological Processes' Models. A.A. 2022/23, INGEGNERIA BIOMEDICA. Titolare del corso
- Scuola GNB. A.A. 2021/22, INGEGNERIA BIOMEDICA. Titolare del corso
- Sistemi biomimetici. A.A. 2021/22, INGEGNERIA BIOMEDICA. Collaboratore del corso
- Ingegneria per la medicina rigenerativa. A.A. 2021/22, INGEGNERIA BIOMEDICA. Titolare del corso
- Laboratory of Tissues and Physiological Processes' Models. A.A. 2021/22, INGEGNERIA BIOMEDICA. Titolare del corso
- Scuola GNB. A.A. 2020/21, INGEGNERIA BIOMEDICA. Titolare del corso
- Sistemi biomimetici. A.A. 2020/21, INGEGNERIA BIOMEDICA. Collaboratore del corso
- Ingegneria per la medicina rigenerativa. A.A. 2020/21, INGEGNERIA BIOMEDICA. Titolare del corso
- Formazione pratica in nanotecnologie biomediche e terapie avanzate. A.A. 2020/21, INGEGNERIA BIOMEDICA. Collaboratore del corso
- New advances in alternative preclinical trials. A.A. 2020/21, INGEGNERIA BIOMEDICA. Titolare del corso
- Ingegneria per la medicina rigenerativa. A.A. 2019/20, INGEGNERIA BIOMEDICA. Titolare del corso
- Ingegneria per la medicina rigenerativa/Bioreattori (modulo di Ingegneria per la medicina rigenerativa). A.A. 2019/20, INGEGNERIA BIOMEDICA. Titolare del corso
- Formazione pratica in nanotecnologie biomediche e terapie avanzate. A.A. 2019/20, INGEGNERIA BIOMEDICA. Collaboratore del corso
- Sistemi biomimetici. A.A. 2019/20, INGEGNERIA BIOMEDICA. Collaboratore del corso
- New advances in alternative preclinical trials. A.A. 2019/20, INGEGNERIA BIOMEDICA. Titolare del corso
- Frontiers in Bioengineering enabling nanotechnologies. A.A. 2018/19, INGEGNERIA BIOMEDICA. Collaboratore del corso
- Sistemi biomimetici. A.A. 2018/19, INGEGNERIA BIOMEDICA. Collaboratore del corso
- Ingegneria per la medicina rigenerativa/Bioreattori (modulo di Ingegneria per la medicina rigenerativa). A.A. 2018/19, INGEGNERIA BIOMEDICA. Titolare del corso
- Formazione pratica in nanotecnologie biomediche e terapie avanzate. A.A. 2018/19, INGEGNERIA BIOMEDICA. Collaboratore del corso
Bachelor of Science
- Ingegneria delle cellule e dei tessuti. A.A. 2024/25, INGEGNERIA BIOMEDICA. Titolare del corso
- Ingegneria delle cellule e dei tessuti. A.A. 2023/24, INGEGNERIA BIOMEDICA. Titolare del corso
- Ingegneria delle cellule e dei tessuti. A.A. 2022/23, INGEGNERIA BIOMEDICA. Titolare del corso
- Ingegneria delle cellule e dei tessuti. A.A. 2021/22, INGEGNERIA BIOMEDICA. Titolare del corso
- Ingegneria delle cellule e dei tessuti. A.A. 2020/21, INGEGNERIA BIOMEDICA. Titolare del corso
- Ingegneria delle cellule e dei tessuti. A.A. 2019/20, INGEGNERIA BIOMEDICA. Titolare del corso
- Ingegneria delle cellule e dei tessuti. A.A. 2018/19, INGEGNERIA BIOMEDICA. Titolare del corso
Research
Research groups
Research projects
Projects funded by competitive calls
- MERIT - Engineered in vitro models of human cardiac fibrotic tissue for the preclinical assessment of the safety and target efficiency of RNA nanotherapies., (2024-2025) - Responsabile Scientifico
PNRR – Mission 4 - EMPATIC - Engineered multi-well platforms integrating biochemical and biophysical cues for the functional maturation and electrophysiological monitoring of cardiac tissue models (EMPATIC), (2024-2025) - Responsabile Scientifico
UE-funded research - HE - Excellent Science - ERC - NANOMIRC - Hybrid polymer-lipid nanoparticles for cell-targeted delivery of reprogramming microRNAs to revert cardiac fibrosis, (2024-2025) - Responsabile Scientifico
PNRR – Mission 4 - NAPTER - Nanoparticelle polimeriche ibride per una terapia con RNA nella cura di patologie cardiache: scale-up della produzione e validazione preclinica (NAPTER), (2023-2025) - Responsabile Scientifico
PNRR – Mission 4 - RECOVERY: pREcise Cardiac Organ-on-chip modeling to improve extracellular VEsicle-based paracrine therapy against myocaRdial Injury, (2023-2025) - Responsabile Scientifico
PNRR – Mission 4 - POLIRNA - Kits for advanced polymer-lipid nanocarriers for targeted delivery of RNAs to cardiac and skeletal muscle cells, (2023-2025) - Responsabile Scientifico
UE-funded research - HE - Excellent Science - ERC - DESIRE - Design and validation of an advanced delivery system for miRNAs and stem cell-derived extracellular vesicles for direct cardiac reprogramming through a mechanically-stimulated human cardiac scar model - DESIRE, (2023-2025) - Responsabile Scientifico
Nationally funded research - PRIN - NanoCARD - Nanoparticelle polimeriche ibride per una terapia a base di microRNA per la rigenerazione cardiaca: percorso di avvicinamento all’applicazione clinica (NanoCARD)., (2023-2024) - Responsabile Scientifico
Corporate-funded and donor-funded research - PACGEL - Plasma-ACtivated hydroGEL: new frontiers solutions in cardiac regenerative medicine, (2023-2025) - Responsabile Scientifico
UE-funded research - HE - Excellent Science - MSCA - SaveAR - Development of a therapeutic strategy to suppress LSD1 and PRMT6-mediated toxic gain of function in SBMA, (2023-2025) - Responsabile Scientifico
Non-EU international research - POLHYGENTH - Nanoparticelle polimeriche ibride per una nuova generazione di vettori non virali per terapia genica nella rigenerazione cardiaca (POLHYGENTH)., (2022-2023) - Responsabile Scientifico
Corporate-funded and donor-funded research - Visco3DCell- Sviluppo di una Metodologia non-Invasiva per lo studio delle proprietà Viscoelastiche di Colture Cellulari 3D., (2021-2022) - Responsabile Scientifico
Corporate-funded and donor-funded research - BIORECAR - ERC-2017-COG, (2018-2023) - Responsabile Scientifico
UE-funded research - H2020 - Excellent Science - ERC - MATERIALI BIOARTIFICIALI E SCAFFOLD BIOMIMETICI PER LA TERAPIA A BASE DI CELLULE STAMINALI NELLA RIGENERAZIONE DEL MIOCARDIO, (2012-2015) - Responsabile Scientifico
Nationally funded research - FIRB
Projects funded by commercial contracts
- Convenzione di ricerca ex art. 15 L. 241/1990 tra il Politecnico di Torino – Dipartimento di Ingegneria Meccanica e Aerospaziale (DIMEAS) e l’Università degli Studi di Torino – Dipartimento di Scienze Chirurgiche (DSC) e Dipartimento di Scienze Mediche (DSM), (periodo sconosciuto) - Responsabile Scientifico
Departmental agreements
Supervised PhD students
- Martina Coletto. Programme in Bioingegneria E Scienze Medico-chirurgiche (39th cycle, 2023-in progress)
- Giovanni Paolo Stola. Programme in Bioingegneria E Scienze Medico-chirurgiche (38th cycle, 2022-in progress)
Research subject: Advanced therapies by bioengineering tools
Bionanotechnology Bionanotechnology Bionanotechnology - Daniele Testore. Programme in Bioingegneria E Scienze Medico-chirurgiche (37th cycle, 2021-in progress)
Research subject: Engineered microenvironment with biomimetic cues for cardiac regeneration
Nanomedicine Bionanotechnology Micro-, meso- and nanostructured materials for advanced therapies Materials, surfaces and biofabrication techniques for tissue engineering and advanced implants - Francesca Tivano. Programme in Bioingegneria E Scienze Medico-chirurgiche (37th cycle, 2022-in progress)
Research subject: Green technologies and materials for the development of eco/biocompatible systems for drug delivery
Medical Innovation and Technology Nanomedicine Bionanotechnology Micro-, meso- and nanostructured materials for advanced therapies Materials, surfaces and biofabrication techniques for tissue engineering and advanced implants Medical Innovation and Technology Nanomedicine Bionanotechnology Micro-, meso- and nanostructured materials for advanced therapies Materials, surfaces and biofabrication techniques for tissue engineering and advanced implants Medical Innovation and Technology Nanomedicine Bionanotechnology Micro-, meso- and nanostructured materials for advanced therapies Materials, surfaces and biofabrication techniques for tissue engineering and advanced implants - Elettra Ugliono. Programme in Bioingegneria E Scienze Medico-chirurgiche (37th cycle, 2021-in progress)
Thesis: Developing scaffolds for full-thickness esophageal replacement
Colorectal & Digestive Surgery Robotic surgery Medical Innovation and Technology Materials, surfaces and biofabrication techniques for tissue engineering and advanced implants Colorectal & Digestive Surgery Robotic surgery Medical Innovation and Technology Materials, surfaces and biofabrication techniques for tissue engineering and advanced implants Colorectal & Digestive Surgery Robotic surgery Medical Innovation and Technology Materials, surfaces and biofabrication techniques for tissue engineering and advanced implants - Letizia Nicoletti. Programme in Bioingegneria E Scienze Medico-chirurgiche (36th cycle, 2020-2024)
Thesis: NEW ADVANCED THERAPIES FOR DRUG DELIVERY IN CARDIAC REGENERATION.
Cardiac and Vascular Surgery Nanomedicine Bionanotechnology Cardiac and Vascular Surgery Nanomedicine Bionanotechnology - Roberta Pappalardo. Programme in Bioingegneria E Scienze Medico-chirurgiche (36th cycle, 2020-2024)
Thesis: Design of injectable hydrogels and nanogels relying on Schiff-base crosslinking of custom-made poly(ether urethane)s and photo-cured methacryloyl gelatin for in situ drug delivery and biological tissue mimics
Bionanotechnology Materials, surfaces and biofabrication techniques for tissue engineering and advanced implants Bionanotechnology Materials, surfaces and biofabrication techniques for tissue engineering and advanced implants Bionanotechnology Materials, surfaces and biofabrication techniques for tissue engineering and advanced implants - Gerardina Ruocco. Programme in Bioingegneria E Scienze Medico-chirurgiche (36th cycle, 2020-2024)
Thesis: Bioartificial scaffolds with biomimetic fibrous structure in the design of in vitro models of cardiac fibrotic and skeletal muscle tissue
Bionanotechnology Cardiovascular Engineering Materials, surfaces and biofabrication techniques for tissue engineering and advanced implants Bionanotechnology Cardiovascular Engineering Materials, surfaces and biofabrication techniques for tissue engineering and advanced implants - Mattia Spedicati. Programme in Bioingegneria E Scienze Medico-chirurgiche (36th cycle, 2020-2024)
Thesis: Fused deposition modelling supporting the design of in vitro models of diseased muscular tissues
Medical Innovation and Technology Nanomedicine Bionanotechnology Cardiovascular Engineering Micro-, meso- and nanostructured materials for advanced therapies Materials, surfaces and biofabrication techniques for tissue engineering and advanced implants Medical Innovation and Technology Nanomedicine Bionanotechnology Cardiovascular Engineering Micro-, meso- and nanostructured materials for advanced therapies Materials, surfaces and biofabrication techniques for tissue engineering and advanced implants
Other activities and projects related to research
COORDINATION OF RESEARCH PROJECTS
1. PROJECT ERC-CoG 2017: BIORECAR (contract number: 772168) “Direct cell reprogramming therapy in myocardial regeneration through an engineered multifunctional platform integrating biochemical instructive cues” (2018-2023). www.biorecar.polito.it
2. Project BIOMODE “In Vitro Experimental Models for Biomaterials-Mediated Drug Delivery to the Central Nervous System” - Compagnia di San Paolo (2017-2021). In collaboration with Prof. R.D. Kamm, Massachussets – MIT.
3. Project “Proof of concepts” Compagnia di San Paolo: “Method for the preparation of cellularised constructs based on thermosensitive hydrogels” (2017).
4. Project PAD-INJ “Smart Injectable Drug-Delivery systems for Parkinson’s and Alzheimer’s Disease Treatment”- Compagnia di San Paolo (2014-2016). In collaboration with Prof. M.G. Spillantini, University of Cambridge (UK).
5. Project FIRB 2010: STARIGEN “Bioartificial materials and biomimetic scaffolds for a stem cells-based therapy for myocardial regeneration” (2012-2015). Overall budget: €1.062.600 (financed grant: € 835.620).
6. Project MITOR - Compagnia di San Paolo: NANOCAB “In Vitro Modelling of Nanoparticle-Mediated Drug Delivery to the Central Nervous System by a Microfluidic Platform Mimicking the Biological Barriers” (2016-2017).
7. Project of Finalized Sanitary Research – 2008 bis, PIEDMONT REGION: “Nano-structured biomimetic coatings for regenerative medicine” (2008-2009)
8. Project of Finalized Sanitary Research – 2009, PIEDMONT REGION: “Multifunctional nano-coatings for medical devices with improved anti-inflammatory and antibacterial properties” (2009-2011).
PARTICIPATION TO RESEARCH PROJECTS
1. PROJECT CRT Visco3DCell (2021-2023). Budget: € 33.000. Role: Collaborator.
2. 2020-NMBP-TR-IND-2018 - Project EVPRO (2019-2022); € 500.000. Role: Task Leader. http://www.evpro-implant.eu/
3. H2020-MSCA ITN-2014 - Project HyMedPoly (2015-2018). Role: WP Leader. https://hymedpoly.eu/
4. BANDO ATENEO-CSP 2014 PROJECT -BIOSURF (2015-2017). Role: Unit Leader.
Publications
PoliTO co-authors
Last years publications
Publications by type
Latest publications View all publications in Porto@Iris
- Spedicati, Mattia; Zoso, Alice; Mortati, Leonardo; Chiono, Valeria; Marcello, Elena; ... (2024)
Three-Dimensional Microfibrous Scaffold with Aligned Topography Produced via a Combination of Melt-Extrusion Additive Manufacturing and Porogen Leaching for In Vitro Skeletal Muscle Modeling. In: BIOENGINEERING, vol. 11. ISSN 2306-5354
Contributo su Rivista - Spedicati, Mattia; Tivano, Francesca; Zoso, Alice; Bei, Janira; Lavella, Mario; ... (2024)
3D bioartificial stretchable scaffolds mimicking the mechanical hallmarks of human cardiac fibrotic tissue. In: INTERNATIONAL JOURNAL OF BIOPRINTING. ISSN 2424-8002
Contributo su Rivista - Marcello, Elena; Zoso, Alice; Ruocco, Gerardina; Chiono, Valeria (2024)
Alginate and Gelatin-based hydrogels for 3D bioprinting of skeletal muscle tissue. In: Annual Meeting of the Italian Society for Biomaterials
Contributo in Atti di Convegno (Proceeding) - Tivano, Francesca; Marcello, Elena; Paoletti, Camilla; Carmagnola, Irene; Mattu, Clara; ... (2024)
Novel drug delivery systems for regenerative medicine applications for perspectivevalorization of agricultural-derived waste products. In: 12th World Biomaterials Congress (WBC), Daegu (South Korea)
Contributo in Atti di Convegno (Proceeding) - Coletto, Martina; Paoletti, Camilla; Nicoletti, Letizia; Stola, GIOVANNI PAOLO; Mattu, ... (2024)
Hybrid nanoparticles for targeted microRNA delivery to cardiomyocytes. In: Controlled Release Society CRS 2024 Annual Meeting and Exposition, Bologna (IT), July, 8-12, 2024
Contributo in Atti di Convegno (Proceeding) - Tivano, Francesca; Paoletti, Camilla; Mattu, Clara; Chiono, Valeria (2024)
Sustainable drug delivery systems for regenerative medicine applications. In: 19th annual event of European Technology Platform on Nanomedicine (ETPN2024), Milano (IT)
Contributo in Atti di Convegno (Proceeding) - Tivano, Francesca; Hinchliffe, Jonathan; Amadi, Elliot; Marcello, Elena; Carmagnola, ... (2024)
Green anti-oxidant drug delivery system based on bacterial cellulose for wound healing applications. In: Annual Meeting of the Italian Society for Biomaterials 2024, Faenza (IT)
Contributo in Atti di Convegno (Proceeding) - Testore, Daniele; Zoso, Alice; Paoletti, Camilla; Marcello, Elena; Chiono, Valeria (2024)
Bio-orthogonally double cross-linked alginate-gelatin hydrogels with tunable viscoelasticity for cardiac tissue engineering. In: Congresso Nazionale Società Italiana Biomateriali - SIB2024 – 08 luglio – 10 luglio 2024, Museo Internazionale delle Ceramiche, Faenza, Italia
Contributo in Atti di Convegno (Proceeding) - Ruocco, Gerardina; Marcello, Elena; Paoletti, Camilla; Zoso, Alice; Carmagnola, Irene; ... (2024)
"Engineered fiber-based anisotropic microenvironments for 2D and 3D in vitro models of skeletal muscle tissues". In: SIB2024-Faenza
Contributo in Atti di Convegno (Proceeding) - Spedicati, Mattia; Zoso, Alice; Mortati, Leonardo; Chiono, Valeria; Marcello, Elena; ... (2024)
3D Aligned Microfibrous Scaffold for Skeletal Muscle Modeling. In: SIB 2024, Faenza (IT)
Contributo in Atti di Convegno (Proceeding) - Marcello, Elena; Stola, GIOVANNI PAOLO; Paoletti, Camilla; Nicoletti, Letizia; Chiono, ... (2024)
Time dependent Alginate Dialdehyde-Gelatin bioinks for cardiac regeneration. In: 12th World Biomaterials Congress, WBC2024, Daegu, Korea
Contributo in Atti di Convegno (Proceeding) - Marcello, Elena; Ruocco, Gerardina; Sanna, Francesca; Zoso, Alice; Carmagnola, Irene; ... (2024)
Nano-fiber reinforced hydrogels for 3D bioprinting of anisotropic tissue. In: 12th World Biomaterials Congress, WBC2024, Daegu, Korea, 26-31/05/2025
Contributo in Atti di Convegno (Proceeding) - Coletto, Martina; Ruocco, Gerardina; Nicoletti, Letizia; Paoletti, Camilla; Zoso, Alice; ... (2024)
Biomimetic In Vitro Model of Human Cardiac Replacement Fibrosis: a Preclinical Testing Platform to assess the Safety and Target Efficiency of Precision Nanomedicine for Cardiac Regeneration. In: 2024 Summer Immersion on Innovative Approaches in Science, Washington DC (USA), May 30 - June 1, 2024
Contributo in Atti di Convegno (Proceeding) - Spedicati, Mattia; Carmagnola, Irene; Lavella, Mario; Tivano, Francesca; Zoso, Alice; ... (2023)
3D Melt-fabricated bio-hybrid scaffolds for the in vitro modelling of human cardiac fibrosis. In: ESB2023 Conference - Davos
Contributo in Atti di Convegno (Proceeding) - Stola, Giovanni Paolo; Marcello, Elena; Paoletti, Camilla; Nicoletti, Letizia; Chiono, ... (2023)
Natural polymer-based bioinks exploiting internal gelation mechanism for cardiac tissue engineering. In: VIII Congress of the National Group of Bioengineering (GNB), pp. 515-517. ISBN: 9788855580113
Contributo in Atti di Convegno (Proceeding) - Visone, Roberta; Paoletti, Camilla; Cordiale, Alessandro; Nicoletti, Letizia; Divieto, ... (2023)
In vitro mechanical stimulation to reproduce the pathological hallmarks of human cardiac fibrosis on a beating chip and predict the efficacy of drugs and advanced therapies. In: ADVANCED HEALTHCARE MATERIALS. ISSN 2192-2659
Contributo su Rivista - Paoletti, Camilla; Nicoletti, Letizia; Marcello, Elena; Zoso, Alice; Stola, GIOVANNI ... (2023)
Injectable hydrogels loaded with hybrid nanoparticles for cell/tissue specific microRNA delivery: towards novel advanced therapies for cardiac regeneration. In: 33rd Annual Conference of the European Society for Biomaterials, Davos (CH), September, 4-8, 2023
Contributo in Atti di Convegno (Proceeding) - Marcello, Elena; Nicoletti, Letizia; Paoletti, Camilla; Stola, GIOVANNI PAOLO; Chiono, ... (2023)
Self-healing and injectable alginate-based hydrogel for microRNA delivery to promote cardiac regeneration after myocardial infarction. In: International N.I.C.E. RENDEZ-VOUS 2023, Nice/Online, 20-22 Giugno 2023
Contributo in Atti di Convegno (Proceeding) - Marcello, Elena; Stola, GIOVANNI PAOLO; Paoletti, Camilla; Nicoletti, Letizia; Chiono, ... (2023)
Time-dependent natural polymer-based bioinks for cardiac tissue engineering. In: Congresso Nazionale Società Italiana Biomateriali SIB 2023, Camerino, 3-6 Luglio
Contributo in Atti di Convegno (Proceeding) - Zoso, A.; Tivano, F.; Spedicati, M.; Lavella, M.; Carmagnola, I.; Chiono, V. (2023)
3D In Vitro Modelling Of Human Cardiac Fibrotic Tissue Through Bio-hybrid Stretchable Scaffolds. In: 7th TERMIS World Congress, Seattle, WA (USA), June 25–28, 2024
Contributo in Atti di Convegno (Proceeding) - Testore, Daniele; Zoso, Alice; Paoletti, Camilla; Groppo, Sara; Marcello, Elena; ... (2023)
Bio-orthogonal double-crosslinked alginate-gelatin/MXenes hydrogels as biomimetic viscoelastic and electroconductive substrates supporting cardiac regeneration. In: 33rd Annual Conference of the European Society for Biomaterials (ESB 2023)
Contributo in Atti di Convegno (Proceeding) - Spedicati, M.; Zoso, A.; Carmagnola, I.; Chiono, V. (2023)
In vitro model of the human esophageal epithelium by tissue engineering tools. In: Fourth Centro 3R Annual Meeting - The role of 3Rs in the age of One Health: where we are and where we’re going, Milano (IT)
Contributo in Atti di Convegno (Proceeding) - Marcello, Elena; Nicoletti, Letizia; Paoletti, Camilla; Chiono, Valeria (2022)
Injectable hydrogels for microRNA delivery to promote direct cell reprogramming in cardiac regeneration. In: 32nd Anuual Conference of the European Society for Biomaterials ESB 2022, Bordeaux, 4-8 Settembre
Contributo in Atti di Convegno (Proceeding) - Testore, Daniele; Zoso, Alice; Kortaberria, Galder; Sangermano, Marco; Chiono, Valeria (2022)
Electroconductive photo-curable PEGDA-Gelatin/PEDOT:PSS hydrogels for prospective cardiac tissue engineering application. In: Tissue Engineering and Regenerative Medicine International Society (TERMIS) European Chapter Conference 2022
Contributo in Atti di Convegno (Proceeding) - Testore, Daniele; Zoso, Alice; Kortaberria, Galder; Sangermano, Marco; Chiono, Valeria (2022)
PEGDA-Gelatin/PEDOT:PSS hydrogels as electroconductive and 3D-printable scaffolds for cardiac tissue engineering. In: International Conference on Biofabrication 2022, September 25th - 28th 2022, Montecatini, Italy
Contributo in Atti di Convegno (Proceeding) - Laurano, Rossella; Boffito, Monica; Pappalardo, Roberta; Chiono, Valeria; Ciardelli, ... (2022)
3D printed bone tissue-mimicking constructs as in vitro preclinical testing platform. In: International conference on biofabrication 2022, Montecatini Terme, Italia, 25-28 Settembre 2022
Contributo in Atti di Convegno (Proceeding) - Laurano, Rossella; Boffito, Monica; Chiono, Valeria; Ciardelli, Gianluca (2022)
Customized thiol-ene photo-click inks: tuning the mechanical properties based on the -ene moiety. In: International conference on biofabrication 2022, Montecatini Terme, Italia, 25-28 Settembre 2022
Contributo in Atti di Convegno (Proceeding) - Laurano, Rossella; Boffito, Monica; Cassino, Claudio; Chiono, Valeria; Ciardelli, ... (2022)
Green approaches to develop patient-specific drug-releasing patches for chronic wound treatment. In: European Summit of Industrial Biotechnology - ESIB 2022, Graz, Austria, 12-14 Novembre 2022
Contributo in Atti di Convegno (Proceeding) - Stola, GIOVANNI PAOLO; Marcello, Elena; Paoletti, Camilla; Nicoletti, Letizia; Chiono, ... (2022)
Alginate Dialdehyde-Gelatin based inks for bioprinting in cardiac tissue engineering. In: International Conference on Biofabrication 2022, Montecatini, 25 - 28 Settembre 2022
Contributo in Atti di Convegno (Proceeding) - Marcello, Elena; Nicoletti, Letizia; Paul, Geo; Cassino, Claudio; Marchese, Leonardo; ... (2021)
Injectable hydrogels for the delivery of miRNA-loaded lipoplexes in cardiac regeneration. In: Congresso Nazionale Biomateriali 2021, Lecce/Online, 11-14 Luglio 2021
Contributo in Atti di Convegno (Proceeding)
Society and Enterprise
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