Giuseppe Cutietta

Ph.D. candidate in Bioingegneria E Scienze Medico-chirurgiche , 41^st cycle (2025-2028)
Department of Mechanical and Aerospace Engineering (DIMEAS)

Adjunct lecturer/Adjunct instructor

giuseppe.cutietta@polito.it

Profile

PhD

Research topic

Multifunctional self-healing hydrogels for drug delivery and tissue regeneration

Tutors

Keywords

Medical Innovation and Technology

Bionanotechnology

Cardiovascular Engineering

Micro-, meso- and nanostructured materials for advanced therapies

Materials, surfaces and biofabrication techniques for tissue engineering and advanced implants

Biography

I am currently pursuing my Ph.D. in Bioengineering and Medical-Surgical Sciences at the Department of Mechanical and Aerospace Engineering (DIMEAS) of Politecnico di Torino. My doctoral research focuses on the development of multifunctional self-healing injectable hydrogels for drug delivery and tissue regeneration, with particular emphasis on applications in chronic and complex tissue injuries. The aim of my work is to design adaptable, bioactive hydrogel systems that can conform to irregular tissue geometries while enabling the controlled release of therapeutic agents, thereby supporting vascularized tissue regeneration and improving healing outcomes. This research is conducted within the framework of the Horizon Europe INJECTHEAL project (Grant agreement ID: 101177924).
My academic path began with a Bachelor’s Degree in Biomedical Engineering, obtained in July 2022. I then pursued a Master’s Degree in Biomedical Engineering, which I completed in March 2025 with a specialization in bionanotechnologies. During my Master thesis, carried out as part of the PACGEL European project (Grant agreement ID: 101067882), I focused on the development of chitosan-based hydrogels as regulatory systems for cardiac diseases, which allowed me to gain extensive hands-on experience in hydrogel synthesis. Following my graduation, I continued at Politecnico di Torino as a Post-graduate Fellow, where I contributed to the development of engineered in vitro models of human cardiac fibrotic tissue for the preclinical assessment of the safety and target efficiency of RNA nanotherapies, within the framework of the PNRR MERIT project (Mission 4) and also to the preclinical validation of polymer-lipid hybrid nanoparticles for a reprogramming therapy in post-infarct cardiac regeneration, within the framework of the PNRR RECHARGE project (Mission 4). This role enabled me to expand my expertise while developing skills in multidisciplinary teamwork.