Duration: da 01/2023 a 12/2025
Scientific Coordinator: Gabriella Olmo
Project Type: Project funded by competitive grant
PoliTO Role: Scientific partner
The project aims to create a technological support to help clinicians estimate the probability of evolution from MCI (Mild Cognitive Impairment) to full-blown dementia, and the differential diagnosis of different types of dementia (Alzheimer's, fronto-temporal, Lewy bodies, etc.).
To this end, a clinical trial is being conducted in which patients with MCI undergo CSF sampling to identify protein markers of Alzheimer's disease (beta-amyloid, tau protein), which constitutes the ‘ground truth’ for diagnosis. In parallel, patients are subjected to cognitive tests, during which physiological parameters are measured and video footage is taken to assess their emotional activation, which is well known to be correlated with the different subtypes of dementia but is not currently assessed as part of the dementia diagnosis protocol.
Involved Structure
- DAUIN, Department of Control and Computer Engineering
Partner
- Department of Neuroscience, University of Turin
- LINKS Foundation, Turin
- Department of Neurology, Molinette Hospital, Dementia Clinic, Turin
Location
- Turin, Italy
Project Team
- Gabriella Olmo (DAUIN), scientific project manager
- Letizia Bergamasco (Fondazione Links)
- Dr. Innocenzo Rainero, Department of Neuroscience, University of Turin and Molinette Hospital - Dementia Clinic
Sustainable Development Goals (SDGs)
3. Good health and well-being