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Valeria Chiono

Full Professor (L. 240)
Department of Mechanical and Aerospace Engineering (DIMEAS)

  • Member of Interdepartmental Center PolitoBIOMed Lab - Biomedical Engineering Lab
  • Vice Coordinator Academic Board - Ph.D. programme in Bioengineering and Medical-Surgical Sciences

Profile

Keywords

3d bioprinting
Advanced drug delivery
Antimicrobial materials
Biomimetic functionalization
Cardiac tissue engineering
In vitro models
Nanomedicine
Non-viral gene therapy
Skin tissue engineering
Tissue engineering

Curriculum

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Scientific branch

IBIO-01/A - Bioengineering
(Area 0009 - Industrial and information engineering)

Research topics

  • Antimicrobial coatings based on bacterial biosurfactants or biomimetic strategies
  • Cardiac tissue engineering: design of biomimetic scaffolds for a stem cells-based therapy in cardiac regeneration
  • Design of biomimetic materials by the preparation of bioartificial blends or surface functionalization of synthetic polymer scaffolds with bioactive molecules.
  • Direct cell reprogramming applied to cardiac regeneration: preparation of nanoparticles for oligonucleotide release and injectable hydrogels for an in situ therapy of infarcted cardiac tissue.
  • Drug releasing hydrogels: preparation of hydrogels based on synthetic and/or natural polymers encapsulating drugs for a controlled and sustained release.
  • In vitro tissue models: blood brain barrier and blood vessels on a chip; engineered cardiac fibrotic tissue; healthy and pathological (mimicking chronic wounds) skin tissue
  • Non-viral gene therapy: lipid and/or polymer nanoparticles for the release of oligonucleotide agents (e.g., siRNAs and miRNAs)
  • Preparation of systems for drug release by green technologies, making use of polymers prepared by bacterial fermentation on by-products of the food industry, or derived from waste products from agricolture, and avoiding or minimizing the use of organic solvents.
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Skills

ERC sectors

LS7_5 - Applied gene and cell therapies, regenerative medicine
PE8_13 - Industrial bioengineering
PE8_13 - Industrial bioengineering
PE8_8 - Materials engineering (biomaterials, metals, ceramics, polymers, composites, etc.)
PE8_8 - Materials engineering (metals, ceramics, polymers, composites, etc.)

SDG

Goal 3: Good health and well-being
Goal 12: Responsible consumption and production

Awards and Honors

  • BioPmed Award 2014 - Gold conferred by BioPmed (2014)
  • Back Cover in Advanced Healthcare Materials conferred by Advanced Healthcare Materials - Wiley (2020)

Fellowships

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Editorial boards

  • MICRO (2021-), Editorial board member
  • FRONTIERS IN BIOMATERIALS SCIENCE (2021-), Other editorial activities
  • FRONTIERS IN PHARMACOLOGY (2021-), Other editorial activities
  • BIOMEDICAL MATERIALS (2020-), Editorial board member
  • FRONTIERS IN CARDIOVASCULAR MEDICINE (2020-), Other editorial activities
  • FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY (2018-), Associate Editor of magazine or editorial series
  • 4 OPEN (2018-), Editorial board member
  • BIOMEDICAL SCIENCE AND ENGINEERING (2016-), Director
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Conferences

  • I Convegno Nazionale SIOoC2023 (4/5/2023-5/5/2023), Program committee
  • International Congress on Biofabrication 2022 (1/1/2022-28/9/2022), Program chair
  • III Convegno Annuale "L'era delle 3R: modelli in silico, in vitro e in vivo per promuovere la ricerca traslazionale" (30/9/2021-1/10/2021), Chairman of the organizing committee
  • XL Scuola Annuale di Bioingegneria 2021 “Biofabrication: an integrated bioengineering approach for the automated fabrication of biological structures for clinical and research applications” (13/9/2021-16/9/2021), Participation to the organizing committee
  • CANCERTO - "Nanoscience in Cancer Immunotherapy" (9/3/2021-11/3/2021), Participation to the organizing committee
  • Workshop “Biology and bioengineering tools in the treatment of H2020 age-related diseases”, Chairman of the organizing committee
  • Workshop "Engineered Biomaterials and Biomedical Devices in the Regenerative Medicine of the Nervous System" (19/11/2015-20/11/2015), Chairman of the organizing committee
  • CONGRESSO SOCIETÀ ITALIANA BIOMATERIALI 2013 (3/6/2013-5/6/2013), Participation to the organizing committee
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Other titles

  • Membro della Giunta DIMEAS 2019-2023 (2019-)
  • Referente di Ateneo per l'Azione del PNRR: Centro Nazionale 3 "Sviluppo di terapia genica e farmaci con tecnologia a RNA" (2021-)
  • Valutazione carriere per studenti che accedono alla Laurea Magistrale in Ingegneria Biomedica - Politecnico di Torino (2021-)
  • Commissario per l'Abilitazione Scientifica Nazionale (ASN) - Settore Concorsuale 09/G2 - Bioingegneria (2021-)
  • Tutor accademico di studenti Erasmus Incoming - Facoltà di Ingegneria Biomedica, Politecnico di Torino (2016-2021)

Research networks

Roles as evaluator or expert

  • First Call of the ADMIRE Marie Skłodowska-Curie Action COFUND in Advanced Materials Research.. 2021
    TRINITY COLLEGE DUBLIN
  • REMOTE REVIEW ERC GRANTS. 2021
    ERC - EUROPEAN RESEARCH COUNCIL - EXECUTIVE AGENCY
  • REMOTE REVIEW ERC GRANTS. 2020
    ERC - EUROPEAN RESEARCH COUNCIL - EXECUTIVE AGENCY

Non-commercial collaboration agreements

Teaching

Collegi of the PhD programmes

  • BIOINGEGNERIA E SCIENZE MEDICO-CHIRURGICHE, 2025/2026 (41. ciclo)
    Politecnico di TORINO
  • BIOINGEGNERIA E SCIENZE MEDICO-CHIRURGICHE, 2024/2025 (40. ciclo)
    Politecnico di TORINO
  • BIOINGEGNERIA E SCIENZE MEDICO-CHIRURGICHE, 2023/2024 (39. ciclo)
    Politecnico di TORINO
  • BIOINGEGNERIA E SCIENZE MEDICO-CHIRURGICHE, 2022/2023 (38. ciclo)
    Politecnico di TORINO
  • BIOINGEGNERIA E SCIENZE MEDICO-CHIRURGICHE, 2021/2022 (37. ciclo)
    Politecnico di TORINO
  • BIOINGEGNERIA E SCIENZE MEDICO-CHIRURGICHE, 2020/2021 (36. ciclo)
    Politecnico di TORINO
  • BIOINGEGNERIA E SCIENZE MEDICO-CHIRURGICHE, 2019/2020 (35. ciclo)
    Università degli Studi di TORINO
  • BIOINGEGNERIA E SCIENZE MEDICO-CHIRURGICHE, 2018/2019 (34. ciclo)
    Università degli Studi di TORINO
  • BIOINGEGNERIA E SCIENZE MEDICO-CHIRURGICHE, 2017/2018 (33. ciclo)
    Università degli Studi di TORINO
  • BIOINGEGNERIA E SCIENZE MEDICO-CHIRURGICHE, 2016/2017 (32. ciclo)
    Politecnico di TORINO
  • BIOINGEGNERIA E SCIENZE MEDICO-CHIRURGICHE, 2015/2016 (31. ciclo)
    Politecnico di TORINO
  • BIOINGEGNERIA E SCIENZE MEDICO-CHIRURGICHE, 2014/2015 (30. ciclo)
    Politecnico di TORINO
MostraNascondi collegi passati

Collegi of the degree programmes

Teachings

PhD

MostraNascondi A.A. passati

Master of Science

MostraNascondi A.A. passati

Bachelor of Science

MostraNascondi A.A. passati

Research

Research groups

Research projects

Projects funded by competitive calls

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Projects funded by commercial contracts

Supervised PhD students

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Other activities and projects related to research

COORDINATION OF RESEARCH PROJECTS

1. PROJECT ERC-CoG 2017: BIORECAR (contract number: 772168) “Direct cell reprogramming therapy in myocardial regeneration through an engineered multifunctional platform integrating biochemical instructive cues” (2018-2023). www.biorecar.polito.it
2. Project BIOMODE “In Vitro Experimental Models for Biomaterials-Mediated Drug Delivery to the Central Nervous System” - Compagnia di San Paolo (2017-2021). In collaboration with Prof. R.D. Kamm, Massachussets – MIT.
3. Project “Proof of concepts” Compagnia di San Paolo: “Method for the preparation of cellularised constructs based on thermosensitive hydrogels” (2017).
4. Project PAD-INJ “Smart Injectable Drug-Delivery systems for Parkinson’s and Alzheimer’s Disease Treatment”- Compagnia di San Paolo (2014-2016). In collaboration with Prof. M.G. Spillantini, University of Cambridge (UK).
5. Project FIRB 2010: STARIGEN “Bioartificial materials and biomimetic scaffolds for a stem cells-based therapy for myocardial regeneration” (2012-2015). Overall budget: €1.062.600 (financed grant: € 835.620).
6. Project MITOR - Compagnia di San Paolo: NANOCAB “In Vitro Modelling of Nanoparticle-Mediated Drug Delivery to the Central Nervous System by a Microfluidic Platform Mimicking the Biological Barriers” (2016-2017).
7. Project of Finalized Sanitary Research – 2008 bis, PIEDMONT REGION: “Nano-structured biomimetic coatings for regenerative medicine” (2008-2009)
8. Project of Finalized Sanitary Research – 2009
, PIEDMONT REGION: “Multifunctional nano-coatings for medical devices with improved anti-inflammatory and antibacterial properties” (2009-2011).

PARTICIPATION TO RESEARCH PROJECTS

1. PROJECT CRT Visco3DCell (2021-2023). Budget: € 33.000. Role: Collaborator.
2. 2020-NMBP-TR-IND-2018 - Project EVPRO (2019-2022); € 500.000. Role: Task Leader. http://www.evpro-implant.eu/
3. H2020-MSCA ITN-2014 - Project HyMedPoly (2015-2018). Role: WP Leader. https://hymedpoly.eu/
4. BANDO ATENEO-CSP 2014 PROJECT -BIOSURF (2015-2017). Role: Unit Leader.

Publications

PoliTO co-authors

Last years publications

Publications by type

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Knowledge Valorisation

Technology transfer