Assegnista di Ricerca
Dipartimento di Ingegneria Meccanica e Aerospaziale (DIMEAS)
Profilo
Interessi di ricerca
Biografia
João C. Silva completed his PhD in Bioengineering Cell Therapies & Regenerative Medicine in September 2019 (with Distinction and Honor - >top 2% students) under the scope of a collaborative international and multidisciplinary project between the Center for Biotechnology and Interdisciplinary Studies (CBIS) from Rensselaer Polytechnic Institute (RPI, United States) and the Institute for Bioengineering and Biosciences (iBB) from Instituto Superior Técnico (IST)-University of Lisbon. Throughout his PhD, which comprised a period as a visiting scholar at RPI (Feb 2017-Dec 2018), João C. Silva developed research work in different areas such as Tissue Engineering and Regenerative Medicine, Material Science Engineering, Stem Cell Biology and Additive Manufacturing. João C. Silva also holds a Masters Degree in Biomedical Engineering (Dec 2013), during which he had the opportunity to gain international experience through an Erasmus exchange program grant to study at Czech Technical University of Prague (Sep 2011-Feb 2012). During his MSc thesis (Feb 2013-Dec 2013), he developed research work in the areas of Molecular Biology and Biotechnology focusing on gene delivery strategies to modulate stem cell differentiation. Afterward, João C. Silva worked as a researcher in 3B's Research Group, University of Minho (Jun 2014-Jan 2015). João C. Silva is currently an MSCA postdoctoral fellow at Politecnico di Torino and a Visiting Researcher at IBB-IST. His research interests focus mainly on: i) tailoring biomaterials structure and composition to mimic stem cell microenvironments; ii) development of novel biomimetic and bioactive scaffold-based approaches for improved tissue regeneration; iii) design and prototyping of bioreactor devices for the fabrication of tissue-engineered constructs under controlled in vivo-like biophysical stimulation. João C. Silva (h-index:18; >1200 citations) has published 44 peer-reviewed articles and 17 conference papers in international scientific journals. He is also the author of 1 book chapter, 1 encyclopedia entry, co-author of 1 patent(WO2015151030A1), and presented his work in more than 30 international scientific conference meetings (31 oral/30 poster presentations). João C. Silva is currently the responsible for the EU MSCA project SYNERGIES and PI of the FCT project InSilico4OCReg(PTDC/EME-SIS/0838/2021, 250 K €). He was/is also an active member of other 9 FCT-funded projects (Funding: 1.65 M €). João C. Silva is a member of the Reviewer Board for the journals Polymers and Frontiers in Bioengineering and Biotechnology and has reviewed articles for 65+ scientific journals in the fields of Biomaterials and Regenerative Medicine (Acta Biomate., Adv. Science, ACS Applied Bio Materials, Mater. Sci. Eng C, Sci. Rep.). João Silva also served as special issue guest-editor for the journals Polymers ("Advanced Polymeric Scaffolds for Stem Cell Engineering and Regenerative Medicine"), International Journal of Bioprinting ("Bioprinting-based strategies for regenerative medicine, drug development and food technology applications") and Frontiers in Bioengineering and Biotechnology ("Advanced bioprocessing strategies for tissue engineering and disease modelling applications"). He is a member of the scientific organizations American Chemical Society (ACS), European Orthopaedic Research Society (EORS), CellAgri Portugal and European Biomechanics Society(ESB). João Silva's academic partners include researchers from RPI (USA), University of Nottingham (UK), UPC-Barcelona Tech(Spain), Center for Rapid and Sustainable Product Development (CDRSP)-IPLeiria(PT) and Centro de Investigação Interdisciplinar Egas Moniz (CiiEM, PT). He works also in close collaboration with a clinical partner (Dr. Nuno A. Ribeiro - orthopedic surgeon at Hospital de Lusíadas, Lisboa) and with industrial partners the healthcare companies Bioceramed and CERAMED-Medical Coatings, which work in the manufacturing of biomaterial devices for orthopedic applications. His supervision experience includes 6 PhD(ongoing), 1 research fellowship, and 12 MSc Thesis (7 concluded/5 ongoing) and the mentoring of the research activities of 2 BSc, 11 MSc and 7 PhD students. He was also part of the jury committee as the main arguer of 7 Master theses in the Bioengineering Department at IST-ULisboa and 2 PhD thesis at ICBAS-Univ. Porto. João C. Silva lectured classes of 1 MSc course(Biomaterials Technology, MSc in Biomedical Engineering), 2 PhD courses(Advanced Experimental Techniques and Methodologies in Biomedical Engineering and Materials for Regenerative Medicine-PhD in Bioengineering) and 1 PhD Advanced Course on "Stem Cell Technologies"(Faculty of Pharmacy-ULisboa). He was also awarded 12 awards/distinctions, including the recent ON Foundation Education Grant Award, the Portugal-UK Bilateral Research Fund 2021 Grant award (Visiting Scholar at Bioelectronics lab-Univ. of Nottingham) and Lab2Market innovation acceleration program 2021 Finalist (Everis/IST).
Competenze
Settori ERC
SDG
Partecipazioni scientifiche
- Fellow (riconoscimento scientifico) - European Society of Biomechanics, Europeo (2024-)
European Society of Biomechanics - Fellow (riconoscimento scientifico) - ESB-ITA: Italian Chapter of the European Society of Biomechanics, Italia (2024-)
ESB-ITA: Italian Chapter of the European Society of Biomechanics - Fellow (riconoscimento scientifico) - CENTRO 3R, Italia (2024-)
Centro Interuniversitario per la Promozione dei Principi delle 3R nella Didattica e nella Ricerca (CENTRO 3R) - Fellow (riconoscimento scientifico) - European Orthopaedic Research Society (EORS), Europeo (2023-)
European Orthopaedic Research Society (EORS) - Responsabile Scientifico - CellAgri Portugal – Associação Portuguesa para o Desenvolvimento da Agricultura Celular – Public Awareness and Dissemination Group coordinator, Portogallo (2022-)
- Fellow (riconoscimento scientifico) - American Chemical Society (ACS), Stati Uniti (2017-)
American Chemical Society: Division of Polymeric Materials Science and Engineering
Comitati editoriali
- FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY (2023-), Guest Editor di rivista o collana editoriale
- INTERNATIONAL JOURNAL OF BIOPRINTING (2023-), Membro del Comitato Editoriale
- INTERNATIONAL JOURNAL OF BIOPRINTING (2022-), Guest Editor di rivista o collana editoriale
- POLYMERS (2022-), Membro del Comitato Editoriale
- POLYMERS (2021-), Guest Editor di rivista o collana editoriale
Pubblicazioni
Coautori PoliTO
Pubblicazioni degli ultimi anni
Pubblicazioni per tipo
Pubblicazioni più recenti Vedi tutte le pubblicazioni su Porto@Iris
- Silva, J. C.; Meneses, J.; Garrudo, F. F. F.; Fernandes, S. R.; Alves, N.; Ferreira, F. ... (2024)
Direct coupled electrical stimulation towards improved osteogenic differentiation of human mesenchymal stem/stromal cells: a comparative study of different protocols. In: SCIENTIFIC REPORTS, vol. 14. ISSN 2045-2322
Contributo su Rivista - Silva, J. C.; Marques, D. M. C.; Tosini, M.; Cabral, J. M. S.; Massai, D.; Ferreira, F. ... (2024)
Edible algae-based decellularized scaffolds as a promising platform towards novel cellular agriculture products. In: 2nd International Conference of Cellagri Portugal, Lisboa, 4-5 October 2024
Contributo in Atti di Convegno (Proceeding) - Silva, J. C.; Marcelino, P.; Barbos, a. F.; Garrudo, F.; Ferreira, F. C. (2024)
Additive manufactured electroactive scaffolds combined with biophysical stimulation towards improved bone tissue engineering strategies. In: International Materials Science and Engineering Congress – MSE 2024, Darmstadt, 24-26 September 2024
Contributo in Atti di Convegno (Proceeding) - Santos, Mafalda S.; Cabral, Joaquim M. S.; Ferreira, F. C; da Silva, C. L; Carvalho, ... (2024)
ELECTROSPUN MEMBRANES WITH ENHANCED BIOACTIVITY FOR PERIODONTAL TISSUE ENGINEERING APPLICATIONS. In: Italian Chapter of the European Society of Biomechanics 2024, Pescara, 3 - 4 October 2024
Contributo in Atti di Convegno (Proceeding) - Silva, J. C.; Garrudo, F.; Marcelino, P.; Meneses, M.; Barbos, a. F.; Alves, N; Massai, ... (2024)
3D PRINTED CONDUCTIVE SCAFFOLDS COMBINED WITH ELECTRICAL STIMULI FOR IMPROVED BONE TISSUE ENGINEERING STRATEGIES. In: Congress of the European Society of Biomechanics (ESB 2024), Edinburgh, 30 June - 4 July 2024
Contributo in Atti di Convegno (Proceeding) - Silva, J. C.; Ferreira, F. C. (2024)
Advanced Polymeric Scaffolds for Stem Cell Engineering and Regenerative Medicine. In: POLYMERS, vol. 16. ISSN 2073-4360
Contributo su Rivista - Domingues, M. F.; Silva, J. C.; Sanjuan-Alberte, P. (2024)
From Spheroids to Bioprinting: A Literature Review on Biomanufacturing Strategies of 3D In Vitro Osteosarcoma Models. In: ADVANCED THERAPEUTICS, vol. 7. ISSN 2366-3987
Contributo su Rivista - Barbosa, F.; Garrudo, F. F. F.; Alberte, P. S.; Resina, L.; Carvalho, M. S.; Jain, A.; ... (2023)
Hydroxyapatite-filled osteoinductive and piezoelectric nanofibers for bone tissue engineering. In: SCIENCE AND TECHNOLOGY OF ADVANCED MATERIALS, vol. 24. ISSN 1468-6996
Contributo su Rivista - Oliveira, A. S.; Silva, J. C.; Loureiro, M. V.; Marques, A. C.; Kotov, N. A.; Colaco, ... (2023)
Super-Strong Hydrogel Composites Reinforced with PBO Nanofibers for Cartilage Replacement. In: MACROMOLECULAR BIOSCIENCE, vol. 23. ISSN 1616-5187
Contributo su Rivista - Santos, M. S.; Carvalho, M. S.; Silva, J. C. (2023)
Recent Advances on Electrospun Nanofibers for Periodontal Regeneration. In: NANOMATERIALS, vol. 13. ISSN 2079-4991
Contributo su Rivista - Garrudo, F. F. F.; Filippone, G.; Resina, L.; Silva, J. C.; Barbosa, F.; Ferreira, L. F. ... (2023)
Production of Blended Poly(acrylonitrile): Poly(ethylenedioxythiophene):Poly(styrene sulfonate) Electrospun Fibers for Neural Applications. In: POLYMERS, vol. 15. ISSN 2073-4360
Contributo su Rivista - Marcelino, P.; Silva, J. C.; Moura, C. S.; Meneses, J.; Cordeiro, R.; Alves, N.; ... (2023)
A Novel Approach for Design and Manufacturing of Curvature-Featuring Scaffolds for Osteochondral Repair. In: POLYMERS, vol. 15. ISSN 2073-4360
Contributo su Rivista - Barbosa, F.; Garrudo, F. F. F.; Marques, A. C.; Cabral, J. M. S.; Morgado, J.; Ferreira, ... (2023)
Novel Electroactive Mineralized Polyacrylonitrile/PEDOT:PSS Electrospun Nanofibers for Bone Repair Applications. In: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, vol. 24. ISSN 1422-0067
Contributo su Rivista - Almeida, D.; Sanjuan-Alberte, P.; Silva, J. C.; Ferreira, F. C. (2023)
3D (bio)printing of magnetic hydrogels: Formulation and applications in tissue engineering. In: INTERNATIONAL JOURNAL OF BIOPRINTING, vol. 10, pp. 1-19. ISSN 2424-8002
Contributo su Rivista - Sanjuan-Alberte, P.; Whitehead, C.; Jones, J. N.; Silva, J. C.; Carter, N.; Kellaway, ... (2022)
Printing biohybrid materials for bioelectronic cardio-3D-cellular constructs. In: ISCIENCE, vol. 25. ISSN 2589-0042
Contributo su Rivista - Oliveira, A. S.; Ferreira, I.; Branco, A. C.; Silva, J. C.; Costa, C.; Nolasco, P.; ... (2022)
Development of polycarbonate urethane-based materials with controlled diclofenac release for cartilage replacement. In: JOURNAL OF BIOMEDICAL MATERIALS RESEARCH. PART B, APPLIED BIOMATERIALS., vol. 110, pp. 1839-1852. ISSN 1552-4973
Contributo su Rivista - Biscaia, S.; Silva, J. C.; Moura, C.; Viana, T.; Tojeira, A.; Mitchell, G. R.; ... (2022)
Additive Manufactured Poly(ε-caprolactone)-graphene Scaffolds: Lamellar Crystal Orientation, Mechanical Properties and Biological Performance. In: POLYMERS, vol. 14. ISSN 2073-4360
Contributo su Rivista - Cordeiro, R.; Henriques, M.; Silva, J. C.; Antunes, F.; Alves, N.; Moura, C. (2022)
Corncob Cellulose Scaffolds: A New Sustainable Temporary Implant for Cartilage Replacement. In: JOURNAL OF FUNCTIONAL BIOMATERIALS, vol. 13. ISSN 2079-4983
Contributo su Rivista - Marques, D. M. C.; Silva, J. C.; Serro, A. P.; Cabral, J. M. S.; Sanjuan-Alberte, P.; ... (2022)
3D Bioprinting of Novel κ-Carrageenan Bioinks: An Algae-Derived Polysaccharide. In: BIOENGINEERING, vol. 9. ISSN 2306-5354
Contributo su Rivista - Oliveira, A. S.; Silva, J. C.; Figueiredo, L.; Ferreira, F. C.; Kotov, N. A.; Colaco, ... (2022)
High-performance bilayer composites for the replacement of osteochondral defects. In: BIOMATERIALS SCIENCE, vol. 10, pp. 5856-5875. ISSN 2047-4830
Contributo su Rivista - Miguel, F.; Barbosa, F.; Ferreira, F. C.; Silva, J. C. (2022)
Electrically Conductive Hydrogels for Articular Cartilage Tissue Engineering. In: GELS, vol. 8. ISSN 2310-2861
Contributo su Rivista - Barbosa, F.; Ferreira, F. C.; Silva, J. C. (2022)
Piezoelectric Electrospun Fibrous Scaffolds for Bone, Articular Cartilage and Osteochondral Tissue Engineering. In: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, vol. 23. ISSN 1422-0067
Contributo su Rivista - Silva, J. C.; Carvalho, M. S.; Xia, K.; Cabral, J. M. S.; da Silva, C. L.; Ferreira, F. ... (2020)
Glycosaminoglycan disaccharide compositional analysis of cell-derived extracellular matrices using liquid chromatography-tandem mass spectrometry. In: METHODS IN CELL BIOLOGY, vol. 156, pp. 85-106. ISSN 0091-679X
Contributo su Rivista - Carvalho, M. S.; Silva, J. C.; Hoff, C. M.; Cabral, J. M. S.; Linhardt, R. J.; da Silva, ... (2020)
Loss and rescue of osteocalcin and osteopontin modulate osteogenic and angiogenic features of mesenchymal stem/stromal cells. In: JOURNAL OF CELLULAR PHYSIOLOGY, vol. 235, pp. 7496-7515. ISSN 0021-9541
Contributo su Rivista - Meneses, J.; Silva, J. C.; Fernandes, S. R.; Datta, A.; Ferreira, A. C.; Moura, C.; ... (2020)
A multimodal stimulation cell culture bioreactor for tissue engineering: A numerical modelling approach. In: POLYMERS, vol. 12. ISSN 2073-4360
Contributo su Rivista - Moura, C. S.; Silva, J. C.; Faria, S.; Fernandes, P. R.; da Silva, C. L.; Cabral, J. M. ... (2020)
Chondrogenic differentiation of mesenchymal stem/stromal cells on 3D porous poly (ε-caprolactone) scaffolds: Effects of material alkaline treatment and chondroitin sulfate supplementation. In: JOURNAL OF BIOSCIENCE AND BIOENGINEERING, vol. 129, pp. 756-764. ISSN 1389-1723
Contributo su Rivista - Silva, J. C.; Udangawa, R. N.; Chen, J.; Mancinelli, C. D.; Garrudo, F. F. F.; Mikael, ... (2020)
Kartogenin-loaded coaxial PGS/PCL aligned nanofibers for cartilage tissue engineering. In: MATERIALS SCIENCE AND ENGINEERING. C, BIOMIMETIC MATERIALS, SENSORS AND SYSTEMS, vol. 107. ISSN 0928-4931. ISBN 18730191 09284931
Contributo su Rivista - Garrudo, F. F. F.; Udangawa, R. N.; Hoffman, P. R.; Sordini, L.; Chapman, C. A.; Mikael, ... (2019)
Polybenzimidazole nanofibers for neural stem cell culture. In: MATERIALS TODAY CHEMISTRY, vol. 14. ISSN 2468-5194
Contributo su Rivista - Aroso, I. M.; Silva, J. C.; Mano, F.; Ferreira, A. S. D.; Dionisio, M.; Sa-Nogueira, I.; ... (2016)
Dissolution enhancement of active pharmaceutical ingredients by therapeutic deep eutectic systems. In: EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS, vol. 98, pp. 57-66. ISSN 0939-6411
Contributo su Rivista - Silva, J. C.; Barros, A. A.; Aroso, I. M.; Fassini, D.; Silva, T. H.; Reis, R. L.; ... (2016)
Extraction of Collagen/Gelatin from the Marine Demosponge Chondrosia reniformis (Nardo, 1847) Using Water Acidified with Carbon Dioxide - Process Optimization. In: INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH, vol. 55, pp. 6922-6930. ISSN 0888-5885. ISBN 15205045 08885885
Contributo su Rivista