Carla Bosia

ERC sectors

SDG

• Collegio di Ingegneria Elettronica, delle Telecomunicazioni e Fisica. Componente invitato
• Collegio di Ingegneria Meccanica, Aerospaziale e dell'Autoveicolo. Componente invitato

Master of Science

• Inference in biological systems. A.A. 2024/25, PHYSICS OF COMPLEX SYSTEMS (FISICA DEI SISTEMI COMPLESSI). Collaboratore del corso
• Inference in biological systems. A.A. 2023/24, PHYSICS OF COMPLEX SYSTEMS (FISICA DEI SISTEMI COMPLESSI). Collaboratore del corso
• Inference in biological systems. A.A. 2022/23, PHYSICS OF COMPLEX SYSTEMS (FISICA DEI SISTEMI COMPLESSI). Titolare del corso
• Inference in biological systems. A.A. 2021/22, PHYSICS OF COMPLEX SYSTEMS (FISICA DEI SISTEMI COMPLESSI). Collaboratore del corso
• Inference in biological systems. A.A. 2020/21, PHYSICS OF COMPLEX SYSTEMS (FISICA DEI SISTEMI COMPLESSI). Collaboratore del corso
• Inference in biological systems. A.A. 2019/20, PHYSICS OF COMPLEX SYSTEMS (FISICA DEI SISTEMI COMPLESSI). Collaboratore del corso

Bachelor of Science

• Fisica II. A.A. 2024/25, INGEGNERIA MECCANICA. Collaboratore del corso
• Fisica II. A.A. 2023/24, INGEGNERIA MECCANICA. Collaboratore del corso
• Fisica II. A.A. 2022/23, INGEGNERIA MECCANICA. Collaboratore del corso
• Fisica II. A.A. 2020/21, INGEGNERIA BIOMEDICA. Collaboratore del corso
• Fisica II. A.A. 2019/20, INGEGNERIA BIOMEDICA. Collaboratore del corso
• Fisica II. A.A. 2019/20, INGEGNERIA BIOMEDICA. Collaboratore del corso

• Institute of Condensed Matter Physics and Complex Systems (DISAT)

• Statistical Physics and Interdisciplinary Applications (DISAT)

Projects funded by competitive calls

• SIMBAD - Statistical Inference from Multiscale Biological Data: theory, algorithms, applications, (2023-2027) - Componente gruppo di Ricerca
  UE-funded research - HE - Excellent Science - MSCA
• vestibulomics - Vestibulodynia at high resolution: omics approach to improve diagnosis, (2023-2025) - Responsabile Scientifico
  Nationally funded research - PRIN

• Elsi Ferro. Programme in Fisica (36^th cycle, 2020-2024)
  Thesis: Competition and band-pass filtering in biology: modelling and experimental validation in membrane trafficking and post-transcriptional gene regulation

• Ferro, Elsi; Szischik, Candela L.; Cunial, Marta; Ventura, Alejandra C.; De Martino, ... (2025)
  Out-of-Equilibrium ceRNA Crosstalk. In: Computational Biology of Non-Coding RNA : Methods and Protocols / Xin Lai, Shailendra Gupta, Julio Vera Gonzalez, S.L., Humana Press - Springer, pp. 167-193. ISBN: 9781071642894
  Contributo in Volume
• Ferro, Elsi; Tealdi, Simone; Margaria, Jean Piero; De Santis, Maria Chiara; Gozzelino, ... (2025)
  A competition network connects Rab5 and Rab11 GTPases at the surface of endocytic structures. In: ISCIENCE, vol. 28. ISSN 2589-0042
  Contributo su Rivista
• Grob, Alice; Enrico Bena, Chiara; Redwood-Sawyerr, Chileab; Polizzi, Karen; Bosia, ... (2024)
  Simultaneous Plate-Reader Characterization of Promoter Activity and Cell Growth in Engineered Mammalian Cells. In: Synthetic Promoters : Methods and Protocols / Marchisio M.A., S.L., Humana Press - Springer, pp. 85-96. ISBN: 9781071640623
  Contributo in Volume
• Grob, Alice; Enrico Bena, Chiara; Di Blasi, Roberto; Pessina, Daniele; Sood, Matthew; ... (2024)
  Mammalian cell growth characterisation by a non-invasive plate reader assay. In: NATURE COMMUNICATIONS, vol. 15. ISSN 2041-1723
  Contributo su Rivista
• Pérez-Fernández, Bárbara Ariane; Calzadilla, Lisandra; Enrico Bena, Chiara; Del Giudice, ... (2024)
  Sodium acetate increases the productivity of HEK293 cells expressing the ECD-Her1 protein in batch cultures: experimental results and metabolic flux analysis. In: FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY, vol. 12. ISSN 2296-4185
  Contributo su Rivista
• Dora, Tortarolo; Pernice, Simone; Clapero, Fabiana; Valdembri, Donatella; Serini, Guido; ... (2023)
  OmniReprodubileCellAnalysis: a comprehensive toolbox for the analysis of cellular biology data. In: 2023 IEEE International Conference on Bioinformatics and Biomedicine (BIBM), Istanbul (TUR), 05-08 December 2023, pp. 3748-3755. ISBN: 979-8-3503-3748-8
  Contributo in Atti di Convegno (Proceeding)
• Cella, Federica; Perrino, Giansimone; Tedeschi, Fabiana; Viero, Gabriella; Bosia, Carla; ... (2023)
  MIRELLA: a mathematical model explains the effect of microRNA-mediated synthetic genes regulation on intracellular resource allocation. In: NUCLEIC ACIDS RESEARCH, vol. 51, pp. 3452-3464. ISSN 1362-4962
  Contributo su Rivista
• Tealdi, Simone; Ferro, Elsi; Campa, Carlo Cosimo; Bosia, Carla (2022)
  microRNA-Mediated Encoding and Decoding of Time-Dependent Signals in Tumorigenesis. In: BIOMOLECULES, vol. 12. ISSN 2218-273X
  Contributo su Rivista
• Enrico Bena, Chiara; Del Giudice, Marco; Grob, Alice; Gueudré, Thomas; Miotto, Mattia; ... (2021)
  Initial cell density encodes proliferative potential in cancer cell populations. In: SCIENTIFIC REPORTS, vol. 11. ISSN 2045-2322
  Contributo su Rivista
• Ferro, E.; Bosia, C.; Campa, C. C. (2021)
  Rab11-mediated trafficking and human cancers: An updated review. In: BIOLOGY, vol. 10, pp. 1-15. ISSN 2079-7737
  Contributo su Rivista
• Villari, Giulia; Enrico Bena, Chiara; DEL GIUDICE, Marco; Gioelli, Noemi; Sandri, ... (2020)
  Distinct retrograde microtubule motor sets drive early and late endosome transport. In: EMBO JOURNAL, vol. 39. ISSN 1460-2075
  Contributo su Rivista
• Chakraborty, M.; Hu, S.; Visness, E.; Giudice, M. D.; de Martino, A.; Bosia, C.; Sharp, ... (2020)
  MicroRNAs organize intrinsic variation into stem cell states. In: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 117, pp. 6942-6950. ISSN 0027-8424
  Contributo su Rivista
• Ferro, E.; Enrico Bena, C.; Grigolon, S.; Bosia, C. (2020)
  microRNA-mediated noise processing in cells: A fight or a game?. In: COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL, vol. 18, pp. 642-649. ISSN 2001-0370
  Contributo su Rivista
• Ferro, E; Enrico Bena, C; Grigolon, S; Bosia, C (2019)
  From Endogenous to Synthetic microRNA-Mediated Regulatory Circuits: An Overview. In: CELLS, vol. 8. ISSN 2073-4409
  Contributo su Rivista
• Martirosyan, Araks; Del Giudice, Marco; ENRICO BENA, Chiara; Pagnani, Andrea; Bosia, ... (2019)
  Kinetic modelling of competition and depletion of shared miRNAs by competing endogenous RNAs. In: Methods in Molecular Biology / S.N., S.L., Humana Press Inc., pp. 367-409. ISBN: 978-1-4939-8981-2
  Contributo in Volume
• Del Giudice, Marco; Bosia, Carla; Grigolon, Silvia; Bo, Stefano (2018)
  Stochastic sequestration dynamics: A minimal model with extrinsic noise for bimodal distributions and competitors correlation. In: SCIENTIFIC REPORTS, vol. 8. ISSN 2045-2322
  Contributo su Rivista
• Campa, C. C.; Margaria, J. P.; Derle, A.; Del Giudice, M.; De Santis, M. C.; Gozzelino, ... (2018)
  Rab11 activity and PtdIns(3)P turnover removes recycling cargo from endosomes. In: NATURE CHEMICAL BIOLOGY, vol. 14, pp. 801-810. ISSN 1552-4450
  Contributo su Rivista
• ENRICO BENA, Chiara; Alice, Grob; Mark, Isalan; Bosia, Carla; Francesca, Ceroni (2018)
  Commentary: Synthetic addiction extends the productive life time of engineered Escherichia coli populations. In: FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY, vol. 9. ISSN 2296-4185
  Contributo su Rivista
• DEL GIUDICE, Marco; Stefano, Bo; Silvia, Grigolon; Bosia, Carla (2018)
  On the role of extrinsic noise in microRNA-mediated bimodal gene expression. In: PLOS COMPUTATIONAL BIOLOGY, vol. 14. ISSN 1553-7358
  Contributo su Rivista
• Franco, Irene; Johansson, Anna; Olsson, Karl; Vrtacnik, Peter; Lundin, Pär; Helgadottir, ... (2018)
  Somatic mutagenesis in satellite cells associates with human skeletal muscle aging. In: NATURE COMMUNICATIONS, vol. 9. ISSN 2041-1723
  Contributo su Rivista
• Bosia, Carla; Sgrò, Francesco; Conti, Laura; Baldassi, Carlo; Cavallo, Federica; Di ... (2017)
  RNAs competing for microRNAs mutually influence their fluctuations in a highly non-linear microRNA-dependent manner in single cells. In: GENOME BIOLOGY, vol. 18, pp. 17-30. ISSN 1474-760X
  Contributo su Rivista
• Riba, Andrea; Bosia, Carla; El Baroudi, Mariama; Ollino, Laura; Caselle, Michele (2014)
  A Combination of Transcriptional and MicroRNA Regulation Improves the Stability of the Relative Concentrations of Target Genes. In: PLOS COMPUTATIONAL BIOLOGY, vol. 10. ISSN 1553-734X
  Contributo su Rivista
• Bosia, C; Pagnani, Andrea; Zecchina, Riccardo; Bosia, Carla (2013)
  Modelling Competing Endogenous RNA Networks. In: PLOS ONE, vol. 8. ISSN 1932-6203
  Contributo su Rivista
• Ala, U.; Karreth, F. A.; Bosia, C.; Pagnani, Andrea; Taulli, R.; Léopold, V.; Tay, Y.; ... (2013)
  Integrated transcriptional and competitive endogenous RNA networks are cross-regulated in permissive molecular environments. In: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 110, pp. 7154-7159. ISSN 0027-8424
  Contributo su Rivista
• Bosia, Carla; Osella, Matteo; Baroudi, Mariama E.; Corà, Davide; Caselle, Michele (2012)
  Gene autoregulation via intronic microRNAs and its functions. In: BMC SYSTEMS BIOLOGY, vol. 6. ISSN 1752-0509
  Contributo su Rivista
• Baroudi, Mariama; Corà, Davide; Bosia, Carla; Osella, Matteo; Caselle, Michele (2011)
  A curated database of miRNA mediated feed-forward loops involving MYC as master regulator. In: PLOS ONE, vol. 6. ISSN 1932-6203
  Contributo su Rivista
• Osella, Matteo; Bosia, Carla; Corá, Davide; Caselle, Michele (2011)
  The role of incoherent microRNA-mediated feedforward loops in noise buffering. In: PLOS COMPUTATIONAL BIOLOGY, vol. 7. ISSN 1553-734X
  Contributo su Rivista
• El Baroudi, M; Bosia, C; Osella, M; Cora, D; Caselle, M (2011)
  Poster presentation. Gene autoregulation via intronic microRNAs and its functions. In: 36th FEBS Congress of the Biochemistry for Tomorrows Medicine, Torino, JUN 25-30, 2011, pp. 149-149. ISSN 1742-464X
  Contributo in Atti di Convegno (Proceeding)
• Caselle, Michele; Osella, Matteo; Bosia, Carla; El-Baroudi, Mariama; Cora, Davide (2011)
  Poster Presentations, The role of incoherent microRNA-mediated feedforward loops in noise buffering. In: 36th FEBS Congress of the Biochemistry for Tomorrows Medicine, Torino, 25-30 June 2011, pp. 148-148. ISSN 1742-464X
  Contributo in Atti di Convegno (Proceeding)
• Bosia, C.; Caselle, M.; Corá, D. (2010)
  Nucleation dynamics in two-dimensional cylindrical Ising models and chemotaxis. In: PHYSICAL REVIEW E, STATISTICAL, NONLINEAR, AND SOFT MATTER PHYSICS, vol. 81. ISSN 1539-3755
  Contributo su Rivista