Ph.D. candidate in Bioingegneria E Scienze Medico-chirurgiche , 38th cycle (2022-2025)
Department of Mechanical and Aerospace Engineering (DIMEAS)
External Collaborator
International Affairs (INCAM)
External Collaborator
Student, Education and International Affairs (STUDI)
Profile
PhD
Research topic
Managment of biological variability in bioreactors for fermentation
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Research presentation
Research interests
Biography
Solid and Fluid Biomechanics Group, Politecnico di Torino, November 2022 – Present
Supervisors: Prof. Diana Massai and Prof. Alberto Audenino
Project title: “Management of Biological Variability”
The Ph.D. project is in collaboration with DiaSorin S.p.A., aiming to support and improve the production processes in the Bio Raw Material Department.
Research Experience:
- Instituto Superior Técnico de Lisboa, January 2025 – June 2025
Visiting Ph.D. student at iBB (Institute for Bioengineering and Biosciences), Supervisor: Prof. Frederico Ferreira- In vitro experiments for bone and cartilage regeneration
- Use of bioreactors developed by Prof. Diana Massai’s group at Politecnico di Torino
- Fabrication and characterization of novel edible plant-derived scaffolds for applications in fish cellular agriculture
- 300+ hours of experience in human and animal cell culture
- Biological analysis techniques including immunofluorescence, gene expression analysis (RT-qPCR), SEM, and confocal microscopy
- Charité Universitätsmedizin Berlin, April 2022 – October 2022
Research Scientist at AUTEM Therapeutics, Berlin, Germany- In vitro experiments on the effects of electromagnetic fields on different hepatocarcinoma cell types
- Plasmid DNA transfection using competent bacteria
- Data analysis and development of multiparametric dose-response curves
- 100+ hours of cell and bacterial culture experience
- Design and management of experimental plans
- University of Alberta, April 2021 – November 2021
Graduate Research Trainee, Supervisor: Prof. Jacek Tuszynski, Edmonton, Canada- In vitro experiments on the effects of Tumor Treating Fields on cancer cells
- Conducted viability assays and functional tests on cancerous and non-cancerous mammalian cells
- Developed and tested a combined therapy involving magnetic nanoparticles, magnetic fields, and a chemotherapy agent
- Polymerization and labeling of microtubules and actin filaments
- In-depth knowledge of the electrical properties of normal and cancerous human cells
- 1000+ hours of cell culture experience
- 100+ hours of confocal microscopy experience
Education:
Politecnico di Torino, 2019–2021
Master of Science in Biomedical Engineering, Track: Bionanotechnology
- Final dissertation title: “In vitro investigation on the effects on cancer cells of Tumour Treating Fields and a combined therapy of a novel chemotherapy agent with magnetic nanoparticles”
- Awarded a Politecnico di Torino scholarship for studies abroad
- Final grade: 106/110
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ERC sectors
SDG
Research
Research groups
Publications
Latest publications View all publications in Porto@Iris
- Masante, Beatrice; Gabetti, Stefano; Silva, Joao; Putame, Giovanni; Israel, Simone; ... (2025)
Insights into bone and cartilage responses to pulsed electromagnetic field stimulation: a review with quantitative comparisons. In: FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY, vol. 13, pp. 1-26. ISSN 2296-4185
Contributo su Rivista - Gabetti, Stefano; Daou, Farah; Masante, Beatrice; Israel, Simone; Zenobi, Eleonora; ... (2025)
In vitro platform to study bone mechanobiology under fluid-induced shear stress and intermittent pressure. In: 30th Congress of the European Society of Biomechanics, Zürich (CH), 6 – 9 July 2025
Contributo in Atti di Convegno (Proceeding) - Masante, Beatrice; Israel, Simone; Gabetti, Stefano; Putame, Giovanni; Massai, Diana (2024)
Automated electro-mechanical bioreactor for enhancing the maturation of engineered muscle tissues in vitro – A promising avenue for cultivated meat?. In: 11th International Scientific Conference of Cultivated Meat, Maastricht, 17 -19 Novembre 2024
Contributo in Atti di Convegno (Proceeding) - Gabetti, Stefano; Daou, Farah; Masante, Beatrice; Israel, Simone; Zenobi, Eleonora; ... (2024)
Direct perfusion and intermittent pressure bioreactor for mimicking and investigating the bone environment. In: XIII Annual Meeting of the Italian Chapter of the European Society of Biomechanics - ESB-ITA24, Pescara, 3-4 October 2024, pp. 28-28
Contributo in Atti di Convegno (Proceeding) - Gabetti, S; Daou, F; Masante, B; Scatena, E; Zenobi, E; Sanginario, A; Israel, S; ... (2024)
Knowledge-generation Platform For Unravelling Bone Regeneration Mechanisms Induced By Biophysical Stimuli. In: TISSUE ENGINEERING, PART A, vol. 30, pp. S35-S35. ISSN 1937-3341
Contributo su Rivista