Simone Israel

Ph.D. candidate in Bioingegneria E Scienze Medico-chirurgiche , 38th cycle (2022-2025)
Department of Mechanical and Aerospace Engineering (DIMEAS)

External Collaborator
Student, Education and International Affairs (STUDI)

Profile

PhD

Research topic

Managment of biological variability in bioreactors for fermentation

Tutors

Research interests

Medical Innovation and Technology
Bionanotechnology
Multiscale Modelling Methods in Biomechanics
Materials, surfaces and biofabrication techniques for tissue engineering and advanced implants

Biography

Ph.D. Candidate in Bioengineering and medical-surgical science: Solid and Fluid Biomechanics, Group Politecnico di Torino, November 2022-Current. Supervisors: Prof. Diana Massai and Prof. Alberto Audenino. Project title "Managment of biological variability".
The Ph.D. is in collaboration with DiaSorin S.P.A. with the mean to improve the production process in the bio raw material (BRM) department of the company.

Research experience:
Charite´ Universitatmedizin Berlin, April 2022 – October 2022 Research scientist for AUTEM Therapeutics Berlin, Germany
  • In vitro experiments on the effect of electromagnetic fields on different hepatocarcinoma cells.
  • Plasmid DNA transfection via competent bacteria.
  • Data analysis and development of a dose-response curve with different parameters.
  • 100+ hours of cells and bacteria culture.
  • Developing and managing the experiment's plan.
University of Alberta, Supervisor Jacek Tuszynski, April 2021-November 2021 Graduate Research Trainee Edmonton, Canada
  • In vitro experiments of the effect of Tumor Treating Fields on cancer cells.
  • Conducted viability studies and functional assays on cancerous and non-cancerous cells.
  • Developed and tested a combined therapy with magnetic nanoparticles, MF, and a chemotherapy agent.
  • Microtubules and actin polymerization and labelling.
  • Deep knowledge of electrical properties of normal and cancer cells.
  • 1000+ hours of cell culture experience.
  • 100+ hours of confocal microscopy.
Education: Politecnico di Torino, 2019-2021 Master of Science in Biomedical Engineering Torino, Italy, track: Bionanotechnology. Final dissertation title: “In vitro investigation on the effects on cancer cells of tumour treating fields and a combined therapy of a novel chemotherapy agent with magnetic nanoparticles” .
Awarded Politecnico di Torino’s scholarship for studies abroad. Final grade 106/110.

Skills

ERC sectors

LS9_1 - Applied biotechnology (including transgenic organisms, applied genetics and genomics, biosensors, bioreactors, microbiology, bioactive compounds)
LS4_12 - Cancer
LS3_1 - Cell cycle, cell division and growth
PE11_1 - Engineering of biomaterials, biomimetic, bioinspired and bio-enabled materials
PE8_13 - Industrial bioengineering

SDG

Goal 3: Good health and well-being
Goal 4: Quality education
Goal 5: Gender equality
Goal 9: Industry, Innovation, and Infrastructure

Research

Research groups

Publications

Latest publications View all publications in Porto@Iris