Fixed-term assistant professor
Department of Mechanical and Aerospace Engineering (DIMEAS)
Profile
Research interests
Biography
Dr. Marco Cavaglià is currently engaged as a Researcher in Industrial Bioengineering at the Department of Mechanical and Aerospace Engineering at the Polytechnic University of Turin (POLITO), dedicating his studies to innovative research on the state of consciousness, with a particular focus on general anesthesia as a research model. His current research focuses on understanding the molecular mechanisms that regulate brain functions, with a specific interest in the role of lipids in neuronal membranes and their impact on neural dynamics. This area of study promises to open new perspectives on neuroprotection, neuroplasticity, and neurodegenerative diseases. With a basic education in Medicine and Surgery obtained at the University of Turin, and a specialization in Anesthesia and Resuscitation, Dr. Cavaglià has consolidated his career through significant clinical and research experiences, including the direction of the pediatric cardio-surgical program at the Aldo Castaneda Institute in Switzerland. His academic path was enriched by a profound research experience at the Cleveland Clinic Foundation in the USA and by obtaining a Ph.D. from the University of Insubria in Varese. Beyond his research, Dr. Cavaglià serves as an Assistant Professor, actively contributing to teaching in the master courses of Rational Drug Design, covering functional chemistry topics, and in Biomechanical Design, focusing on cellular molecular physiology and an introduction to neuroscience. This blend of teaching and research highlights his commitment to educating the next generations of scientists and bioengineers, providing them with the skills to tackle future challenges in bioengineering and medicine. In his current role, Dr. Cavaglià actively engages in the university's "third mission," promoting scientific dissemination and public education through organizing conferences with the QPP Seralmente association. This commitment reflects his dedication not only to research and clinical practice but also to open dialogue with society, to share scientific discoveries and stimulate greater awareness of brain health
Scientific branch
(Area 0009 - Industrial and information engineering)
Research topics
- Information Theory,Transcendental Meditation and Spiritual Practices: Dr. Marco Cavaglià has conducted extensive research on the efficacy of Transcendental Meditation as per the Maharishi Method and dynamic meditation techniques learned at the Taoist community in Wuhan. This line of research explores the impact of these meditative practices on psychophysical well-being and brain functionality. Additionally, his experiences in Mexico, including the symbolic passage ritual from hummingbird to eagle, reflect a deep interest in spiritual traditions and their connection with modern science. Dr. Cavaglià integrates these studies with an interest in information theory, investigating how information principles can be applied to understanding meditative and spiritual experiences.
- Neuronal Markers of brain injury related to cardiopulmonary bypass.Heart-Brain Interactions in Cardiovascular Surgery: Dr. Cavaglià investigates the complex dynamics between cardiac functions and brain activities, especially within cardiovascular surgery contexts. His research aims at understanding the pathophysiological mechanisms linking heart and brain and finding strategies to mitigate adverse neurological effects from cardiac interventions.
- Technological Innovations in Managing the COVID-19 Pandemic: During the COVID-19 pandemic, Dr. Cavaglià contributed to the development of innovative devices for the non-invasive management of COVID-19 patients. Notably, he worked on a CPAP device project that improves treatment efficacy while aiming to reduce environmental contamination risks and oxygen consumption.
- The Role of Lipids in Brain Functioning: Dr. Cavaglià's interest also extends to the study of lipids in brain cell membranes, with a particular focus on their impact on cognitive and neurological processes. He has published a theoretical paper proposing a novel paradigm for understanding brain functioning, placing lipids at the forefront of scientific discussion in neuroscience.
Skills
ERC sectors
SDG
Open badges
- Learning to Teach (L2T)
Issued by Politecnico di Torino on 16-02-2023
Fellowships
- Effective member - Società Italiana di Anestesia, Analgesia, Rianimazione e Terapia Intensiva (S.I.A.A.R.T.I.), Italia (2022-)
- President - Research Institute for Quantitative and Quantum Dynamics of living Organism, Italia (2019-)
- Executive Committee member - 7HC Technologies, Italia (2019-)
- Effective member - America Society of Anesthesiology, Stati Uniti (1996-)
- Effective member - AAROI-Associazione Anestesisti Rianimatori Ospedalieri Italiani, Italia (1992-)
Conferences
- Organizzazione del congresso annuale di QPP (1/1/2020-20/4/2024), Program chair
- Organizzazione di 4 convegni annuali di libera divulgazione della cultura scientifica presso l'Aula Magna del Politecnico di Torino. (10/10/2019-31/1/2044), Program chair
- Summer School “Brain & Gut Neuroscience: From Molecules to Mood” Three edition 2018-2019-2020 (21/8/2017-24/3/2017), Program committee
Other research or teaching roles outside Politecnico
- Professore Incaricato, presso Università degli Studi del PIEMONTE ORIENTALE (10/9/2001-31/7/2003)
- Titolare di contratto di ricerca, presso Cleveland Clinic Foundation (5/10/1998-2/7/2001)
- Titolare di contratto di ricerca, presso Università degli Studi di TORINO (1/1/1992-1/1/1993)
Other titles
- Invenzione dispositivo per la ventilazione non invasiva a basso consumo di ossigeno in assenza di contaminazione ambientale e deposito di brevetto “Kit di supporto alla respirazione” congiunta tra Politecnico di Torino (50%), APR (40%), Dott. Olivieri 10 (2020-)
- Il premio "Wiley TOP DOWNLOADED ARTICLE" è stato assegnato a Marco Cavaglià per il riconoscimento del suo articolo pubblicato sulla rivista "Artificial Organs" intitolato "Noninvasive mechanical ventilation in the COVID-19 era: Proposal for a continuous p (2021-2044)
Teaching
Collegi of the degree programmes
- Collegio di Ingegneria Biomedica. Componente invitato
Teachings
Master of Science
- Biomechanical design. A.A. 2024/25, INGEGNERIA BIOMEDICA. Collaboratore del corso
- Rational Drug Design: Principles and Applications. A.A. 2024/25, INGEGNERIA BIOMEDICA. Collaboratore del corso
- Biomeccanica multiscala. A.A. 2024/25, INGEGNERIA BIOMEDICA. Collaboratore del corso
- Biomechanical design. A.A. 2023/24, INGEGNERIA BIOMEDICA. Collaboratore del corso
- Biomeccanica multiscala. A.A. 2023/24, INGEGNERIA BIOMEDICA. Collaboratore del corso
- Biomechanical design. A.A. 2022/23, INGEGNERIA BIOMEDICA. Collaboratore del corso
- Biomeccanica multiscala. A.A. 2022/23, INGEGNERIA BIOMEDICA. Collaboratore del corso
- Biomechanical design. A.A. 2021/22, INGEGNERIA BIOMEDICA. Collaboratore del corso
- Biomeccanica multiscala. A.A. 2021/22, INGEGNERIA BIOMEDICA. Collaboratore del corso
Research
Research groups
Research projects
Projects funded by competitive calls
- BRAIN - Validazione di indicatori neurobiologici per la valutazione del benessere di bovini in allevamento intensivo, (2020-2023) - Responsabile Scientifico
National Research
Publications
PoliTO co-authors
Latest publications View all publications in Porto@Iris
- Shah, Syed Taimoor Hussain; Shah, Syed Adil Hussain; Khan, Iqra Iqbal; Imran, Atif; ... (2024)
Data-driven classification and explainable-AI in the field of lung imaging. In: FRONTIERS IN BIG DATA, vol. 7. ISSN 2624-909X
Contributo su Rivista - Cavaglià, Marco; Deriu, Marco A.; Tuszynski, Jack A. (2023)
Toward a holographic brain paradigm: a lipid-centric model of brain functioning. In: FRONTIERS IN NEUROSCIENCE, vol. 17. ISSN 1662-453X
Contributo su Rivista - Cavaglià, Marco; Zizzi, Eric; Dombrowski, Stephen; Deriu, Marco A.; Tuszynski, Jacek (2022)
Alteration of Consciousness by Anaesthetics: A Multiscale Modulation from the Molecular to the Systems Level. In: JOURNAL OF CONSCIOUSNESS STUDIES, vol. 29, pp. 21-49. ISSN 1355-8250
Contributo su Rivista - Zizzi, Eric A.; Cavaglia', Marco; Tuszynski, Jacek A.; Deriu, Marco A. (2022)
Alteration of lipid bilayer mechanics by volatile anesthetics: insights from μs-long molecular dynamics simulations. In: ISCIENCE. ISSN 2589-0042
Contributo su Rivista - Cannariato, Marco; Miceli, Marcello; Cavaglià, Marco; Deriu, Marco A. (2022)
Prediction of Protein–Protein Interactions Between Alsin DH/PH and Rac1 and Resulting Protein Dynamics. In: FRONTIERS IN MOLECULAR NEUROSCIENCE, vol. 14. ISSN 1662-5099
Contributo su Rivista - Miceli, Marcello; Exertier, Cécile; Cavaglià, Marco; Gugole, Elena; Boccardo, Marta; ... (2022)
ALS2-Related Motor Neuron Diseases: From Symptoms to Molecules. In: BIOLOGY, vol. 11. ISSN 2079-7737
Contributo su Rivista - Miceli, Marcello; Exertier, Cecile; Vallone, Beatrice; Cavaglià, Marco; Deriu, Marco A. (2021)
Elucidating molecular connetion between IAHSP onset and Alsin protein by means of Homology Modelling and Molecular Dynamics. In: III Convegno Annuale "L'era delle 3R: modelli in silico, in vitro e in vivo per promuovere la ricerca traslazionale". ISSN 2531-9892
Contributo in Atti di Convegno (Proceeding) - Zizzi, Eric A.; Cavaglia', Marco; Deriu, Marco A.; Tuszynski, Jacek A. (2021)
In silico investigation of molecular interactions of Volatile Anesthetics: Effects on phospholipid membranes and subcellular targets. In: Centro 3R Annual Meeting | September 30th - October 1st, September 30th - October 1st, pp. 123-124
Contributo in Atti di Convegno (Proceeding) - Sperti, Michela; Malavolta, Marta; Ciniero, Gloria; Borrelli, Simone; Cavaglià, Marco; ... (2021)
JAK Inhibitors in Immune-Mediated Rheumatic Diseases: from a Molecular Perspective to Clinical Studies. In: JOURNAL OF MOLECULAR GRAPHICS & MODELLING, vol. 104. ISSN 1093-3263
Contributo su Rivista - Miceli, Marcello; Muscat, Stefano; Morbiducci, Umberto; Cavaglia', Marco; Deriu, MARCO ... (2021)
ULTRASOUND DRIVEN AMYLOID FIBRIL UNFOLDING INVESTIGATED BY MOLECULAR MODELLING. In: 26th Congress of the European Society of Biomechanics, Milan (IT), July 11-14, 2021, pp. 206-206
Contributo in Atti di Convegno (Proceeding)
Society and Enterprise
Patents and other intellectual properties
- DIVOC (REVERSE COVID) - DEVICE FOR NON-INVASIVE VENTILATION WITH LOW OXYGEN CONSUMPTION IN ABSENCE OF ENVIRONMENTAL CONTAMINATION. national and international Patent
Inventors: Alberto Audenino Marco Cavaglia' Alexander Ivanov Umberto Morbiducci Terenziano Raparelli