Staff

Huxiao Shi. Programme in Ingegneria Chimica (38^th cycle, 2022-in progress)
Chidera Winifred Amazu. Programme in Ingegneria Chimica (37^th cycle, 2021-in progress)
Ambra Massei. Programme in Ingegneria Chimica (37^th cycle, 2021-in progress)
Thesis: Spectroscopic Techniques as PAT monitoring Tools for the Development of Biopharmaceutical Product Processes

Machine learning

Freeze drying
Veronica Vighetto. Programme in Ingegneria Chimica (35^th cycle, 2019-2023)
Thesis: The manifold roles of zinc oxide nanocrystals in interaction with acoustic waves

Other activities and projects related to research

The research activity of Davide Fissore is mainly focused on process modelling and on the design and validation of advanced model-based tools for process monitoring and control.

His early research interests focused on the catalytic treatment of lean VOC-air mixtures in thermally and catalytically stabilised combustors, and in forced unsteady-state reactors.

Later, he investigated the possibility of using unsteady-state reactors for synthesis reactions (e.g. syngas production) and for chromatographic process (e.g. the catalytic reduction of NO_x with ammonia). He developed, and validated, both first-principles and black-box models for process control and optimisation, and he proposed advanced monitoring (soft-sensors) and control (Model Predictive Control, Robust Control) systems for these processes.

After getting the PhD degree, the research activity was still focused on the monitoring and control of chemical processes with complex dynamics, and then moved to a different field, i.e. pharmaceutical engineering and, in particular, in applying the "Quality by Design" concept in the field of pharmaceuticals manufacturing. The research was focused on the optimization, monitoring and control of the batch freeze-drying of pharmaceuticals, where he proposed, validated, and, in some cases, patented, original and effective solutions for both the primary and the secondary drying stages.

The application of these methodologies to food freeze-drying was also investigated.

A recent research field is the synthesis and preservation (using freeze-drying) of polymeric nanoparticles for drug delivery and for food fortification. In this framework the research activity has been focused on the optimization of the reactor configuration and of the operating parameters, aiming at maximizing the loading of the desired component, as well as maintaining particles dimension in the desired range. Release of the active ingredient has also been investigated.

Publications

Latest publications View all publications in Porto@Iris

Amazu, Chidera Winifred; Mietkiewicz, Joseph; Abbas, Ammar N.; Baldissone, Gabriele; ... (2024)
Lessons Learnt From Human-In-Loop Experimental Scenarios For Advanced Automation In Process Safety. In: ESREL2024: the 34-th European Safety and Reliability Conference, Cracow (Poland), 23-27 June 2024, pp. 9-18. ISBN: 978-83-68136-04-3
Contributo in Atti di Convegno (Proceeding)
Amazu, CHIDERA WINIFRED; Demichela, Micaela; Fissore, Davide; Leva, MARIA CHIARA (2024)
Comparing Two Control Room Intervention Procedure Formats: Preliminary Insights from Eye Tracking Measures. In: CHEMICAL ENGINEERING TRANSACTIONS, vol. 111, pp. 223-228. ISSN 2283-9216
Contributo su Rivista
Amazu, Chidera W.; Mietkiewicz, Joseph; Abbas, Ammar N.; Briwa, Houda; Alonso-Perez, ... (2024)
Exploring the Influence of Human System Interfaces: Introducing Support Tools and an Experimental Study. In: INTERNATIONAL JOURNAL OF HUMAN-COMPUTER INTERACTION, pp. 1-18. ISSN 1044-7318
Contributo su Rivista
Amazu, Chidera; Mcgrory, John; Chiara Leva, Maria; Baldissone, Gabriele; Fissore, ... (2024)
Human factors in alarm response procedures: An empyrical analysis of paper versus digital support.. In: Proceedings of the 12th International Conference on Human Interaction and Emerging Technologies, IHIET 2024, Venezia (Italia), August 26-28, 2024, pp. 116-125. ISSN 2771-0718. ISBN: 978-1-964867-33-5
Contributo in Atti di Convegno (Proceeding)
Massei, Ambra; Falco, Nunzia; Fissore, Davide (2024)
Use of Raman Spectroscopy and PCA for quality evaluation and out-of-specification identification in biopharmaceutical products. In: EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS, vol. 200. ISSN 0939-6411
Contributo su Rivista

Society and Enterprise

Patents and other intellectual properties

Pirolizzatore continuo polivalente. national Patent
Inventors: Giancarlo Baldi Davide Fissore
Eliminazione del TAR e gassificazione del residuo carbonioso provenienti da pirolisi di sostanze organiche. national Patent
Inventors: Giancarlo Baldi Davide Fissore

Davide Fissore

Full Professor (L. 240) Department of Applied Science and Technology (DISAT)

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