Research database

ConStRAINeD - Convergence and Stability of Reaction and Interaction Network Dynamics (ConStRAINeD)

Duration:
24 months (2023 - 2025)
Principal investigator(s):
Project type:
Nationally funded research - PRIN
Funding body:
MINISTERO (Ministero dell'Università e della Ricerca)
Project identification number:
2022XRWY7W
PoliTo role:
Coordinator

Abstract

The project Convergence and Stability of Reaction and Interaction Network Dynamics (ConStRAINeD) deals with specific Continuous-Time Markov Chain models of interacting individuals called Stochastic Reaction Networks (SRNs). The state space is the number of available individuals of different kinds, and transitions are encoded by a finite set of allowed reactions, which can be arranged as the edges of a reaction graph. SRNs are often utilized as models in biochemistry, epidemiology and ecology. The aim of ConStRAINeD is to provide new theoretical insight on SRNs which are crucial to unlock a deeper understanding in important applications. ConStRAINeD has two main objectives: Objective 1: developing theorems connecting the structure of the reaction graph (RG) with the positive recurrence of the model, as well as with an exact description of the stationary distributions. Objective 2: introducing peculiar spatial dependencies. ConStRAINeD will extend the setting of SRN to cases in which spatial positions of particles are taken into account by introducing a random graph of interaction and diffusion dynamics. The effect that this has on the large volume dynamics will be studied. All the objectives concern theorems based mainly on the structure of the RG and therefore independent on the specific rate parameters. This choice is motivated by the fact that the exact rates of changes in biological, epidemiological or ecological systems are rarely known with precision. Hence, results that hold for any choice of parameters are both impactful and mathematically interesting.

People involved

Departments

Partners

  • POLITECNICO DI MILANO
  • POLITECNICO DI TORINO - Coordinator
  • UNIVERSITA' DI PISA

Keywords

ERC sectors

PE1_13 - Probability
PE1_20 - Application of mathematics in sciences

Budget

Total cost: € 234,249.00
Total contribution: € 187,374.00
PoliTo total cost: € 159,699.00
PoliTo contribution: € 112,824.00