Davide Fissore

Professore Ordinario (L.240)
Dipartimento Scienza Applicata e Tecnologia (DISAT)

  • Componente Commissione istruttoria per il Coordinamento dell'Attività Didattica e formativa
  • Coordinatore Collegio di Ingegneria Chimica e dei Materiali
  • Componente Centro Interdipartimentale R3C - Responsible Risk Resilience Centre

Profilo

Interessi di ricerca

Freeze drying
Image analysis
Nanoparticles
Near infrared spectroscopy
Process control
Process monitoring
Statistical process control
Thermography (imaging)

Linee di ricerca

  • Drug delivery systems based on nanoparticles: the research activity is focused on the optimization of the reactor configuration and of the operating parameters, aiming at maximizing the loading of the desired component, as well as maintaining particles dimension in the desired range. Release of the active ingredient is also investigated.
  • Freeze-drying: Monitoring, control, infrared thermography, Quality by design, The research is focused on the optimization, monitoring and control of the batch freeze-drying of pharmaceuticals, where original and effective solutions for both the primary and the secondary drying stages were proposed, validated and, in some cases, patented. The application of these methodologies to food freeze-drying was also investigated.

Competenze

Settori ERC

PE8_2 - Chemical engineering, technical chemistry
PE8_4 - Computational engineering
PE8_13 - Industrial bioengineering
PE8_9 - Production technology, process engineering

Comitati editoriali

  • PHARMACEUTICS (2021-), Guest Editor di rivista o collana editoriale
  • JOURNAL OF PHARMACEUTICAL SCIENCES (2019-2023), Altro tipo di attività editoriale

Didattica

Collegi di Dottorato

  • INGEGNERIA CHIMICA, 2022/2023 (39. ciclo)
    Politecnico di TORINO
  • INGEGNERIA CHIMICA, 2021/2022 (38. ciclo)
    Politecnico di TORINO
  • INGEGNERIA CHIMICA, 2020/2021 (37. ciclo)
    Politecnico di TORINO
  • INGEGNERIA CHIMICA, 2019/2020 (36. ciclo)
    Politecnico di TORINO
  • INGEGNERIA CHIMICA, 2018/2019 (35. ciclo)
    Politecnico di TORINO
  • INGEGNERIA CHIMICA, 2017/2018 (34. ciclo)
    Politecnico di TORINO
  • INGEGNERIA CHIMICA, 2016/2017 (33. ciclo)
    Politecnico di TORINO
  • INGEGNERIA CHIMICA, 2015/2016 (32. ciclo)
    Politecnico di TORINO
  • INGEGNERIA CHIMICA, 2014/2015 (31. ciclo)
    Politecnico di TORINO
  • INGEGNERIA CHIMICA, 2013/2014 (30. ciclo)
    Politecnico di TORINO
  • INGEGNERIA CHIMICA, 2012/2013 (29. ciclo)
    Politecnico di TORINO
  • INGEGNERIA CHIMICA, 2011/2012 (28. ciclo)
    Politecnico di TORINO
  • INGEGNERIA CHIMICA, 2010/2011 (27. ciclo)
    Politecnico di TORINO
  • INGEGNERIA CHIMICA, 2009/2010 (26. ciclo)
    Politecnico di TORINO
  • INGEGNERIA CHIMICA, 2008/2009 (25. ciclo)
    Politecnico di TORINO
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Collegi dei Corsi di Studio

Insegnamenti

Dottorato di ricerca

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Corso di laurea magistrale

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Corso di laurea di 1° livello

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Progetti di didattica e formazione finanziati da enti esterni

Progetti finanziati da bandi competitivi

Progetti finanziati da contratti commerciali

Ricerca

Istituto

Gruppi/team di ricerca

Laboratori

Progetti di ricerca

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Dottorandi

Altre attività e progetti di ricerca

The research activity of Davide Fissore is mainly focused on process modelling and on the design and validation of advanced model-based tools for process monitoring and control.

His early research interests focused on the catalytic treatment of lean VOC-air mixtures in thermally and catalytically stabilised combustors, and in forced unsteady-state reactors.

Later, he investigated the possibility of using unsteady-state reactors for synthesis reactions (e.g. syngas production) and for chromatographic process (e.g. the catalytic reduction of NOx with ammonia). He developed, and validated, both first-principles and black-box models for process control and optimisation, and he proposed advanced monitoring (soft-sensors) and control (Model Predictive Control, Robust Control) systems for these processes.

After getting the PhD degree, the research activity was still focused on the monitoring and control of chemical processes with complex dynamics, and then moved to a different field, i.e. pharmaceutical engineering and, in particular, in applying the "Quality by Design" concept in the field of pharmaceuticals manufacturing. The research was focused on the optimization, monitoring and control of the batch freeze-drying of pharmaceuticals, where he proposed, validated, and, in some cases, patented, original and effective solutions for both the primary and the secondary drying stages.

The application of these methodologies to food freeze-drying was also investigated.

A recent research field is the synthesis and preservation (using freeze-drying) of polymeric nanoparticles for drug delivery and for food fortification. In this framework the research activity has been focused on the optimization of the reactor configuration and of the operating parameters, aiming at maximizing the loading of the desired component, as well as maintaining particles dimension in the desired range. Release of the active ingredient has also been investigated.

Pubblicazioni

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Società e imprese

Brevetti e altre proprietà intellettuali