Giacomo Antonicelli

Ph.D. candidate in Ingegneria Civile E Ambientale , 37^th cycle (2021-2024)
Department of Environment, Land and Infrastructure Engineering (DIATI)

giacomo.antonicelli@polito.it

Profile

PhD

Thesis title

Valorization of CO2 rich off gas through gas fermentation

Research topic

Development of a gas fermentative process for the valorization of CO2 waste

Tutors

Research presentation

Poster

Research interests

Environmental Quality

Biography

I am an industrial biotechnologist with a focus on developing solutions to 21st-century environmental issues. My research field involves the valorisation of CO2-rich waste gases from environmentally impactful industrial sectors through an innovative and promising approach. During my PhD, I am studying the development of a gas fermentative process to directly convert gaseous CO2 mixed with H2 into high-value liquid products using acetogenic bacteria. The objective of this study is to optimize the process of producing hexanol as the main product using Clostridium carboxidivorans to valorize the mentioned gas mixture. Hexanol is a C6-alcohol that serves as a drop-in molecule for various market segments, including solvents, flavors and fragrances, plasticizers, detergents, coatings, and pharma/fine chemicals. This work proposes substituting the current production of hexanol, which is based on fossil fuels or kernel palm oil, with a commercially and environmentally sustainable bio-based process.

Publications

Latest publications View all publications in Porto@Iris

Ricci, Luca; Cen, Xuecong; Zu, Yuexuan; Antonicelli, Giacomo; Chen, Zhen; Fino, Debora; ... (2025)
Metabolic Engineering of E. coli for Enhanced Diols Production from Acetate. In: ACS SYNTHETIC BIOLOGY, vol. 14, pp. 1204-1219. ISSN 2161-5063
Contributo su Rivista
Antonicelli, G.; Vasile, N.; Piro, E.; Fraterrigo Garofalo, S.; Menin, B.; Verga, F.; ... (2025)
Harnessing an adapted strain of Clostridium carboxidivorans to unlock hexanol production from carbon dioxide and hydrogen in elevated-pressure stirred tank reactors. In: BIORESOURCE TECHNOLOGY, vol. 418. ISSN 0960-8524
Contributo su Rivista
Tarraran, Loredana; Agostino, Valeria; Vasile, Nicolò S.; ABDEL AZIM, Annalisa; ... (2023)
High-pressure fermentation of CO2 and H2 by a modified Acetobacterium woodii. In: JOURNAL OF CO2 UTILIZATION, vol. 76, pp. 1-11. ISSN 2212-9820
Contributo su Rivista
Antonicelli, Giacomo; Ricci, Luca; Tarraran, Loredana; FRATERRIGO GAROFALO, Silvia; Re, ... (2023)
Expanding the product portfolio of carbon dioxide and hydrogen-based gas fermentation with an evolved strain of Clostridium carboxidivorans. In: BIORESOURCE TECHNOLOGY, vol. 387. ISSN 1873-2976
Contributo su Rivista
Di Leonardo, Pier Francesco; Antonicelli, Giacomo; Agostino, Valeria; Re, Angela (2022)
Genome-Scale Mining of Acetogens of the Genus Clostridium Unveils Distinctive Traits in [FeFe]- and [NiFe]-Hydrogenase Content and Maturation. In: MICROBIOLOGY SPECTRUM, vol. 10, pp. 1-24. ISSN 2165-0497
Contributo su Rivista