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Gum-Gut - The microbiome along the gum-gut axis: biobank creation, multiOMICS phenotyping and effect of periodontal treatment (the Gum-Gut Project).
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Abstract
Growing scientific evidence suggests that the oral cavity and the gastrointestinal tract do act as a functional and pathologic continuum. Indeed, there is a need for a deeper characterization of the microbiome-host interaction in these two interconnected anatomical niches in health and disease, together with a longitudinal assessment of potential changes after microbiome-targeted interventions. Therefore, scope of this research is to integrate and compare distinctive multi-specimen, multiOMICS profiles of subjects with oral health and patients with severe periodontitis in order to achieve a better understanding of the physiopathology of the gum-gut axis for future precision medicine applications.
People involved
- Gabriella Balestra (Principal Investigator)
- Samanta Rosati (Component of the research team)
Structures
Partners
- POLITECNICO DI TORINO - AMMINISTRAZIONE CENTRALE
- Università degli Studi di Firenze
- Università degli Studi di TORINO - Coordinator
- Università degli studi di Trento
Keywords
ERC sectors
Sustainable Development Goals
Budget
| Total cost: | € 229,426.00 |
|---|---|
| Total contribution: | € 229,426.00 |
| PoliTo total cost: | € 23,145.00 |
| PoliTo contribution: | € 23,145.00 |