Anagrafe della ricerca

Gum-Gut - The microbiome along the gum-gut axis: biobank creation, multiOMICS phenotyping and effect of periodontal treatment (the Gum-Gut Project).

24 mesi (2023 - 2025)
Responsabile scientifico:
Tipo di progetto:
PNRR – Missione 4
Ente finanziatore:
Codice identificativo progetto:
Ruolo PoliTo:


Growing scientific evidence suggests that the oral cavity and the gastrointestinal tract do act as a functional and pathologic continuum. Indeed, there is a need for a deeper characterization of the microbiome-host interaction in these two interconnected anatomical niches in health and disease, together with a longitudinal assessment of potential changes after microbiome-targeted interventions. Therefore, scope of this research is to integrate and compare distinctive multi-specimen, multiOMICS profiles of subjects with oral health and patients with severe periodontitis in order to achieve a better understanding of the physiopathology of the gum-gut axis for future precision medicine applications.

Persone coinvolte

Dipartimenti coinvolti


  • Università degli Studi di Firenze
  • Università degli Studi di TORINO - Coordinatore
  • Università degli studi di Trento

Parole chiave

Settori ERC

LS2_6 - Molecular genetics, reverse genetics and RNAi
LS2_4 - Metabolomics

Obiettivi di Sviluppo Sostenibile (Sustainable Development Goals)

Obiettivo 3. Assicurare la salute e il benessere per tutti e per tutte le età


Costo totale progetto: € 229.426,00
Contributo totale progetto: € 229.426,00
Costo totale PoliTo: € 23.145,00
Contributo PoliTo: € 23.145,00