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InSilicoHealth aims to train doctoral candidates in the field of virtual human twin technology, with a specific focus on addressing challenges related to healthy aging in Europe in three core domains: heart, musculoskeletal, and brain. There is a two-way transfer between the research projects and the interdisciplinary training programme, in which candidates will receive a broad education that spans different fields relevant to digital health. A compelling interdisciplinary joint degree-DN programme for 11 DCs is proposed answering four interdisciplinary research objectives, shouldered by intersectoral training components (i.e., academic and non-academic secondments) to prepare a new generation of outstanding digital health professionals. InSilicoHealth will provide a comprehensive and forward-looking programme that combines research, interdisciplinary training, and collaboration with industry to address the complex challenges of healthy ageing, using virtual human twin technology. The DCs will be actively encouraged to surpass the technology-driven focus and to explicitly addressing the ethical, legal societal implications of VHT technologies. By providing the DCs with a 360° view on the methodological, technological, ethical, social, and regulatory challenges associated with this digital revolution of healthcare, InSilicoHealth is conceptualized as a steppingstone for a sustainable EU-based, doctoral programme on in silico health.