Dottoranda in Bioingegneria E Scienze Medico-chirurgiche , 37o ciclo (2021-2024)
Dipartimento di Ingegneria Meccanica e Aerospaziale (DIMEAS)
Assegnista di Ricerca
Dipartimento Scienza Applicata e Tecnologia (DISAT)
Docente esterno e/o collaboratore didattico
Dipartimento di Ingegneria Meccanica e Aerospaziale (DIMEAS)
Profilo
Dottorato di ricerca
Argomento di ricerca
Solvent-free nanoparticles for encapsulation of water-soluble compounds for melanoma treatment
Tutori
Presentazione della ricerca
Interessi di ricerca
Biografia
In Semptember 2021, she got a position as a Post-graduate Fellow for the design of experimental in vitro model for drug delivery system validation. On January 2021, she began the PhD program in Bioengineering and Medical-Surgical Sciences under the supervision of Professor Ciardelli and professor Mattu (DM 1061 - NOP 2014-2020 for Doctoral Research programmes with specific reference to Action IV.5 “PhD programmes on sustainability-based topics").
On September 2022 she obtained the State Qualifying Exam at Politecnico di Torino to practice the profession of Industrial Engineer.
Her work is focused on the development of sustainable synthesis techniques to prepare drug-delivery system for metastatic melanoma treatment, that will replace organic solvents with water-based solution, to respond to the increasing need of innovative practices with lower environmental risk, and greener manufacturing in the pharmaceutical industry. At the same time, she is developing a 3D printed vascularised melanoma model which will be exploited for the nanoparticles validation to investigate the tumour's response to the administration of therapeutic siRNA and antibody in a more representative tumor microenvironment.
Didattica
Insegnamenti
Corso di laurea magistrale
- Biomimetic systems. A.A. 2024/25, INGEGNERIA BIOMEDICA. Collaboratore del corso
- Sistemi biomimetici. A.A. 2023/24, INGEGNERIA BIOMEDICA. Collaboratore del corso
- Formazione pratica in nanotecnologie biomediche e terapie avanzate. A.A. 2022/23, INGEGNERIA BIOMEDICA. Collaboratore del corso
Pubblicazioni
Pubblicazioni più recenti Vedi tutte le pubblicazioni su Porto@Iris
- Mattioda, Carlotta; Voena, Claudia; Ciardelli, Gianluca; Mattu, Clara (2025)
In Vitro 3D Models of Haematological Malignancies: Current Trends and the Road Ahead?. In: CELLS, vol. 14. ISSN 2073-4409
Contributo su Rivista - Bezze, Andrea; Mattioda, Carlotta; Ciardelli, Gianluca; Mattu, Clara (2024)
Harnessing cells to improve transport of nanomedicines. In: EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS, vol. 203. ISSN 0939-6411
Contributo su Rivista - Mattioda, Carlotta; Mattu, Clara; Ciardelli, Gianluca (2024)
Development of a vascularized in vitro skin model mimicking metastatic melanoma. In: Congresso Società Italiana Biomateriali 2024, Faenza, 08/07/2024 - 10/07/2024, pp. 88-89
Contributo in Atti di Convegno (Proceeding) - Mattioda, Carlotta; Mattu, Clara; Ciardelli, Gianluca (2023)
Development of green approaches based on solvent-free nanoparticles and in vitro models for the management of metastatic melanoma. In: The role of 3Rs in the age of One Health: where we are and where we’re going., Milano, Italia, September 13-15, 2023, pp. 13-13
Contributo in Atti di Convegno (Proceeding) - Mattioda, Carlotta; Mattu, Clara; Ciardelli, Gianluca (2023)
Green approaches based on solvent-free methods to prepare nanoparticles and on alternative in vitro models for their validation: application in the treatment of metastatic melanoma. In: ESB 2023, Davos, Svizzera, 4-8/09/2023, pp. 675-675
Contributo in Atti di Convegno (Proceeding)