Fixed-term assistant professor
Department of Mechanical and Aerospace Engineering (DIMEAS)
Profile
Research interests
Biography
Giuseppe De Nisco got the PhD in Bioengineering and Medical-Surgical Sciences from Politecnico di Torino in 2018, working in the Computational and Experimental Cardiovascular Biomechanics Unit (Leader: Prof. Umberto Morbiducci) of Industrial Bioengineering research group. After the PhD he carried on his research activities as a post-doctoral fellow at Politecnico di Torino. In 2018 he worked as Visiting Researcher at the Department of Cardiology, Erasmus MC, Rotterdam, the Netherlands in the research group of Prof. Jolanda J. Wentzel. From 2022 he is an Assistant Professor in Industrial Bioengineering at Politecnico di Torino. He was awarded a ESB Travel Award in 2019 from the European Society of Biomechanics, and a VPH Young Researcher Participation Award and a VPH Young Investigator Presentation Award in 2020 from the Virtual Physiological Human Committee. He contributed to the coordination activities of 3 Post-Doctoral research fellows, 5 PhD students, and 40+ graduate students in Biomedical Engineering. He is author of 28 publications in peer-reviewed international scientific journals, and several conference papers. He was involved in research projects in the framework of biomedical engineering, involving both engineering and medical units (National projects: CECOMES (MIUR 2020) - IRMI (MIUR); European project: InSiDe (EU)). His current research focuses on elucidating the associations between blood fluid mechanics, vascular morphometry and cardiovascular disease development, diagnosis and treatment; the clinical translation of these associations; the design and optimization of cardiovascular devices and surgical techniques.
Scientific branch
(Area 0009 - Industrial and information engineering)
Skills
ERC sectors
SDG
Awards and Honors
- ESB Travel Award 2019 conferred by ESB (European Society of Biomecanics), Austria (2019)
- VPH2020 Young Investigator Award conferred by VPH, Belgium (2020)
- VPH2020 Young Researcher Partecipation Award conferred by VPH (Virtual Physiological Human) 2020 Organizing Committee, Francia (2020)
Teaching
Collegi of the degree programmes
- Collegio di Ingegneria Biomedica. Componente invitato
Teachings
PhD
- Biomeccanica dei fluidi e processamento di bioimmagini come ausilio per la diagnostica, il processo decisionale e la definizione di strategie chirurgiche cardiovascolari. A.A. 2022/23, BIOINGEGNERIA E SCIENZE MEDICO-CHIRURGICHE. Teaching assistant
Master of Science
- Progettazione di protesi e organi artificiali. A.A. 2023/24, INGEGNERIA BIOMEDICA. Collaboratore del corso
- Biomeccanica dei solidi/Biomeccanica dei fluidi (modulo di Biomeccanica dei solidi). A.A. 2023/24, INGEGNERIA BIOMEDICA. Collaboratore del corso
- Progettazione di protesi e organi artificiali. A.A. 2022/23, INGEGNERIA BIOMEDICA. Collaboratore del corso
- Biomeccanica dei solidi/Biomeccanica dei fluidi (modulo di Biomeccanica dei solidi). A.A. 2022/23, INGEGNERIA BIOMEDICA. Collaboratore del corso
- Biomeccanica dei solidi/Biomeccanica dei fluidi (modulo di Biomeccanica dei fluidi). A.A. 2021/22, INGEGNERIA BIOMEDICA. Collaboratore del corso
- Biomeccanica dei solidi/Biomeccanica dei fluidi (modulo di Biomeccanica dei solidi). A.A. 2021/22, INGEGNERIA BIOMEDICA. Collaboratore del corso
- Biomeccanica dei solidi/Biomeccanica dei fluidi (modulo di Biomeccanica dei fluidi). A.A. 2020/21, INGEGNERIA BIOMEDICA. Collaboratore del corso
- Biomeccanica dei solidi/Biomeccanica dei fluidi (modulo di Biomeccanica dei solidi). A.A. 2020/21, INGEGNERIA BIOMEDICA. Collaboratore del corso
- Biomeccanica dei solidi/Biomeccanica dei fluidi (modulo di Biomeccanica dei fluidi). A.A. 2019/20, INGEGNERIA BIOMEDICA. Collaboratore del corso
- Biomeccanica dei solidi/Biomeccanica dei fluidi (modulo di Biomeccanica dei solidi). A.A. 2019/20, INGEGNERIA BIOMEDICA. Collaboratore del corso
- Biomeccanica e biodinamica sperimentale/Biomeccanica del sistema cardiovascolare (modulo di Biomeccanica del sistema cardiovascolare). A.A. 2019/20, INGEGNERIA BIOMEDICA. Collaboratore del corso
Bachelor of Science
- Medicina digitale - Intraprendenti. A.A. 2023/24, INGEGNERIA AEROSPAZIALE. Collaboratore del corso
- Medicina digitale - Intraprendenti. A.A. 2022/23, INGEGNERIA AEROSPAZIALE. Collaboratore del corso
Research
Research groups
Research projects
Projects funded by commercial contracts
- Modellazione numerica mediante l’uso di metodi propri della fluidodinamica computazionale del processo industriale di sanificazione di protesi valvolari cardiache, (2024-2024) - Responsabile Scientifico
Commercial contracts for the provision of services
Supervised PhD students
- Bianca Griffo. Programme in Bioingegneria E Scienze Medico-chirurgiche (38th cycle, 2022-in progress)
Research subject: Enhancing fluid dynamics with machine learning
Cardiovascular Engineering Cardiovascular Engineering
Publications
Last years publications
PoliTO co-authors
Publications by type
Last years publications View all publications in Porto@Iris
- Calo, Karol; Capellini, Katia; DE NISCO, Giuseppe; Mazzi, Valentina; Gasparotti, ... (2023)
Modelling aortic flows: impact of wall displacements on large-scale hemodynamic coherence in ascending aorta. In: 28th Congress of the European Society of Biomechanics, Maastricht (NL), July 9-12, 2023, pp. 136-136
Contributo in Atti di Convegno (Proceeding) - Carbonaro, Dario; Mezzadri, Francesco; Ferro, Nicola; DE NISCO, Giuseppe; Audenino, ... (2023)
Design of innovative self-expandable femoral stents using inverse homogenization topology optimization. In: COMPUTER METHODS IN APPLIED MECHANICS AND ENGINEERING. ISSN 0045-7825
Contributo su Rivista - Calo, Karol; Capellini, Katia; De Nisco, Giuseppe; Mazzi, Valentina; Gasparotti, ... (2023)
Impact of wall displacements on the large-scale flow coherence in ascending aorta. In: JOURNAL OF BIOMECHANICS, vol. 154. ISSN 0021-9290
Contributo su Rivista - J Hartman, Eline M; DE NISCO, Giuseppe; M Kok, Annette; Tomaniak, Mariusz; A Nous, Fay ... (2023)
Wall shear stress-related plaque growth of lipid-rich plaques in human coronary arteries: an near-infrared spectroscopy and optical coherence tomography study. In: CARDIOVASCULAR RESEARCH, vol. 119, pp. 1021-1029. ISSN 0008-6363
Contributo su Rivista - DE NISCO, Giuseppe; Hartman, Eline M.; Mazzi, Valentina; Gallo, Diego; Chiastra, ... (2023)
Wall shear stress topological skeleton variability predicts plaque growth in human coronary arteries. In: European Symposium on Vascular Biomaterials (ESVB) 2023, Strasbourg, France, 19-22 April 2023
Contributo in Atti di Convegno (Proceeding) - De Nisco, Giuseppe; Lodi Rizzini, Maurizio; Verardi, Roberto; Chiastra, Claudio; ... (2023)
Modelling blood flow in coronary arteries: Newtonian or shear-thinning non-Newtonian rheology?. In: COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE, vol. 242. ISSN 0169-2607
Contributo su Rivista - Calo, Karol; Capellini, Katia; DE NISCO, Giuseppe; Gallo, Diego; Celi, Simona; ... (2022)
Investigating the impact of wall distensibility on aortic flow using a network-based approach. In: ESB-ITA 2022 XI Annual Meeting, Massa (IT), October 6-7, 2022, pp. 18-18
Contributo in Atti di Convegno (Proceeding) - DE NISCO, Giuseppe; Hartman, Eline M.; Mazzi, Valentina; Gallo, Diego; Chiastra, ... (2022)
The variability of wall shear stress topological skeleton predicts plaque growth in human coronary arteries. In: The 17th international symposium on Biomechanics in Vascular Biology and Cardiovascular Disease, Rotterdam, The Nederlands, April 2022
Contributo in Atti di Convegno (Proceeding) - Chiastra, C.; Mazzi, V.; Lodi Rizzini, M.; Calo', K.; Corti, A.; Acquasanta, A.; De ... (2022)
Coronary Artery Stenting Affects Wall Shear Stress Topological Skeleton. In: JOURNAL OF BIOMECHANICAL ENGINEERING, vol. 144, pp. 1-11. ISSN 0148-0731
Contributo su Rivista - Corti, Anna; Colombo, Monika; De Nisco, Giuseppe; Rodriguez Matas, Jose Felix; ... (2022)
Computational investigation of the role of low-density lipoprotein and oxygen transport in atherosclerotic arteries. In: Modeling of Mass Transport Processes in Biological Media / Becker S., Kuznetsov A., de Monte F., Pontrelli G., Zhao D., S.L., Elsevier, pp. 139-213. ISBN: 9780323857413
Contributo in Volume - Candreva, Alessandro; De Nisco, Giuseppe; Lodi Rizzini, Maurizio; D’Ascenzo, Fabrizio; ... (2022)
Current and Future Applications of Computational Fluid Dynamics in Coronary Artery Disease. In: REVIEWS IN CARDIOVASCULAR MEDICINE, vol. 23. ISSN 1530-6550
Contributo su Rivista - Mazzi, Valentina; De Nisco, Giuseppe; Calo, Karol; Chiastra, Claudio; Daemen, Joost; ... (2022)
Divergence of the normalized wall shear stress as an effective computational template of low-density lipoprotein polarization at the arterial blood-vessel wall interface. In: COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE, vol. 226. ISSN 0169-2607
Contributo su Rivista - DE NISCO, Giuseppe; Hartman, Eline; Mazzi, Valentina; Gallo, Diego; Chiastra, Claudio; ... (2022)
Wall shear stress topological skeleton variability predicts plaque growth in human coronary arteries. In: 27th Congress of the European Society of Biomechanics, Porto (PT), 26 – 29 June 2022
Contributo in Atti di Convegno (Proceeding) - DE NISCO, Giuseppe; Hartman, Eline; Mazzi, Valentina; Gallo, Diego; Chiastra, Claudio; ... (2022)
WALL SHEAR STRESS TOPOLOGICAL SKELETON VARIABILITY PREDICTS ATHEROSCLEROTIC PLAQUE GROWTH IN HUMAN CORONARY ARTERIES. In: Summer Biomechanics, Bioengineering and Biotransport Conference 2022, Eastern Shore, Maryland (USA), June 20-23, 2022, pp. 528-529. ISBN: 978-1-7351808-4-7
Contributo in Atti di Convegno (Proceeding) - Mazzi, V.; De Nisco, G.; Hoogendoorn, A.; Calo', K.; Chiastra, C.; Gallo, D.; Steinman, ... (2021)
Early Atherosclerotic Changes in Coronary Arteries are Associated with Endothelium Shear Stress Contraction/Expansion Variability. In: ANNALS OF BIOMEDICAL ENGINEERING, vol. 49, pp. 2606-2621. ISSN 0090-6964
Contributo su Rivista - De Nisco, G.; Chiastra, C.; Hartman, E. M. J.; Hoogendoorn, A.; Daemen, J.; Calo', K.; ... (2021)
Comparison of Swine and Human Computational Hemodynamics Models for the Study of Coronary Atherosclerosis. In: FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY, vol. 9. ISSN 2296-4185
Contributo su Rivista - DE NISCO, Giuseppe; Mazzi, Valentina; Calo', Karol; LODI RIZZINI, Maurizio; Chiastra, ... (2021)
EULERIAN-BASED WALL SHEAR STRESS TOPOLOGICAL SKELETON AS A TEMPLATE OF NEAR-WALL MASS TRANSPORT IN ARTERIES. In: 26th Congress of the European Society of Biomechanics, Milan (IT) (congresso online), July 11-14, 2021
Contributo in Atti di Convegno (Proceeding) - DE NISCO, Giuseppe; Mazzi, Valentina; Calo', Karol; LODI RIZZINI, Maurizio; Chiastra, ... (2021)
EXPLORING THE LINK BETWEEN WALL SHEAR STRESS TOPOLOGICAL SKELETON AND NEAR-WALL MASS TRANSPORT IN CARDIOVASCULAR FLOWS USING A EULERIAN-BASED METHOD. In: Summer Biomechanics, Bioengineering and Biotransport Conference 2021, Virtual Conference, June 14-18, 2021, pp. 681-682. ISBN: 978-1-7351808-2-3
Contributo in Atti di Convegno (Proceeding) - Hoogendoorn, Ayla; Kok, Annette M; Hartman, Eline M J; de Nisco, Giuseppe; Casadonte, ... (2021)
Multidirectional wall shear stress promotes advanced coronary plaque development: comparing five shear stress metrics. In: CARDIOVASCULAR RESEARCH, vol. 116, pp. 1136-1146. ISSN 0008-6363
Contributo su Rivista - Hartman, E. M. J.; De Nisco, G.; Kok, A. M.; Hoogendoorn, A.; Coenen, A.; Mastik, F.; ... (2021)
Lipid-rich Plaques Detected by Near-infrared Spectroscopy Are More Frequently Exposed to High Shear Stress. In: JOURNAL OF CARDIOVASCULAR TRANSLATIONAL RESEARCH, vol. 14, pp. 416-425. ISSN 1937-5387
Contributo su Rivista - Hartman, Eline M. J.; DE NISCO, Giuseppe; Gijsen, Frank J. H.; Korteland, Suze-Anne; van ... (2021)
The definition of low wall shear stress and its effect on plaque progression estimation in human coronary arteries. In: SCIENTIFIC REPORTS, vol. 11. ISSN 2045-2322
Contributo su Rivista - Mazzi, Valentina; Morbiducci, Umberto; Calo', Karol; De Nisco, Giuseppe; Lodi Rizzini, ... (2021)
Wall shear stress topological skeleton analysis in cardiovascular flows: Methods and applications. In: MATHEMATICS, vol. 9. ISSN 2227-7390
Contributo su Rivista